Survivorship Program, Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue N, Mailstop D5-280, PO Box 19024, Seattle, WA 98109-1024, USA.
Pediatr Clin North Am. 2010 Feb;57(1):323-42. doi: 10.1016/j.pcl.2009.11.008.
Children who survive hematopoietic stem cell transplantation (HSCT) are at risk for an inordinate number of long-term side effects. Late effects can be secondary to the underlying diagnosis for which the transplant is performed, prior treatment of the disease, the transplant preparative regimen, treatment of the complications of transplant, and immunologic interactions between the graft and the host. This article describes the risks and manifestations of the most commonly reported late effects in survivors of pediatric HSCT.
接受造血干细胞移植（HSCT）的儿童存在大量长期副作用的风险。迟发性效应可能继发于移植所针对的基础诊断、疾病的先前治疗、移植准备方案、移植并发症的治疗以及移植物和宿主之间的免疫相互作用。本文描述了儿科 HSCT 幸存者中最常见的迟发性效应的风险和表现。
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