Mau G, Schnakenburg K
Eur J Pediatr. 1977 Aug 23;126(1-2):77-84. doi: 10.1007/BF00443125.
The case histories of 2,362 newborn boys were evaluated for congenital testicular maldescent. These data, obtained from the prospective follow-up study "Pregnancy and Child Development" sponsored by the Deutsche Forschungsgemeinschaft, are discussed in the light of new findings on morphological changes in this disorder. The aetiology of maldescent of testes is considered to be heterogenous and could not be clarified by investigating 26 factors which might be regarded as possible causes of the abnormality. The difficulties in achieving a correct classification of the various forms of maldescended testes are emphasized and are demonstrated by data from this collaborative study. Considering the frequency of non-descent at the ages of 9 months (3.3%), 18 months (2.9%), and 36 months (2.5%), we believe we have found some evidence for spontaneous descent in a proportion of cases during the first 3 years of life. If this is confirmed by proposed new studies, the findings will have to be weighed against the recommendations of the 1974 International Health Foundation that therapy should be performed during the 2nd year of life or earlier.
对2362例男婴的病历进行了先天性睾丸下降不全评估。这些数据来自德国研究基金会资助的前瞻性随访研究“妊娠与儿童发育”，并根据该疾病形态学变化的新发现进行了讨论。睾丸下降不全的病因被认为是异质性的，通过调查26个可能被视为该异常潜在原因的因素，仍无法明确病因。强调了对各种形式的睾丸下降不全进行正确分类的困难，并通过这项合作研究的数据进行了说明。考虑到9个月（3.3%）、18个月（2.9%）和36个月（2.5%）时睾丸未降的发生率，我们认为我们已经找到了一些证据，表明一部分病例在生命的前3年中会出现自发性下降。如果拟议的新研究证实了这一点，那么这些发现将不得不与1974年国际健康基金会的建议进行权衡，该建议认为治疗应在生命的第二年或更早进行。
