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X 线透视引导下球囊扩张治疗头颈部癌放疗后咽食管狭窄。

Fluoroscopically guided balloon dilation for pharyngoesophageal stricture after radiation therapy in patients with head and neck cancer.

机构信息

Department of Radiology, Henan Tumor Hospital, Zhengzhou, Henan Province, People's Republic of China.

出版信息

AJR Am J Roentgenol. 2010 Apr;194(4):1131-6. doi: 10.2214/AJR.09.3345.

Abstract

OBJECTIVE

The purpose of this article is to assess the safety and long-term efficacy of fluoroscopically guided balloon dilation for pharyngoesophageal strictures after radiation therapy in patients with head and neck cancers.

MATERIALS AND METHODS

From April 1997 to February 2009, fluoroscopically guided balloon dilation was performed in 17 patients with pharyngoesophageal strictures caused by radiation therapy. Technical success, clinical success (decrease of at least one grade in dysphagia score and good contrast passage on 1-month follow-up esophagogram), recurrence of dysphagia, and complications related to the procedure were retrospectively evaluated.

RESULTS

All 17 patients underwent 41 balloon dilation procedures, with each patient undergoing one to seven procedures (mean, 2.4 procedures). The technical success rate was 100%, and clinical success was achieved in 64.7% (11/17) of the patients. Five patients (29.4%) showed no recurrence of dysphagia after one session of balloon dilation. Of 12 patients (70.6%) with recurrence of dysphagia, 10 underwent repeat balloon dilation and two underwent gastrostomy after the first session of balloon dilation. The maximum balloon diameters were 15 mm (n = 22), 20 mm (n = 16), and 25 mm (n = 3). As minor complications, three cases of type 1 esophageal rupture occurred in two patients (11.8%). There were no major complications.

CONCLUSION

Although the recurrence rate was high with repeat balloon dilation, fluoroscopically guided balloon dilation seems to be a simple and safe primary treatment technique for pharyngoesophageal stricture due to radiation therapy in patients with head and neck cancer.

摘要

目的

本文旨在评估头颈部癌症患者因放射治疗导致的咽食管狭窄行荧光透视引导下球囊扩张的安全性和长期疗效。

材料和方法

1997 年 4 月至 2009 年 2 月,对 17 例因放射治疗导致的咽食管狭窄患者进行了荧光透视引导下球囊扩张。回顾性评估了技术成功率、临床成功率(吞咽困难评分至少降低一级,1 个月随访食管造影显示良好对比通过)、吞咽困难复发和与该操作相关的并发症。

结果

所有 17 例患者共进行了 41 次球囊扩张,每位患者进行 1 至 7 次(平均 2.4 次)。技术成功率为 100%,17 例患者中有 64.7%(11/17)达到临床成功。5 例(29.4%)患者在单次球囊扩张后无吞咽困难复发。12 例(70.6%)吞咽困难复发的患者中,10 例患者在首次球囊扩张后行重复球囊扩张,2 例患者行胃造口术。最大球囊直径为 15mm(n=22)、20mm(n=16)和 25mm(n=3)。作为轻微并发症,有 2 例患者(11.8%)出现 3 例 1 型食管破裂。无重大并发症。

结论

尽管重复球囊扩张的复发率较高,但对于头颈部癌症患者因放射治疗导致的咽食管狭窄,荧光透视引导下球囊扩张似乎是一种简单且安全的初始治疗技术。

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