Spine and Brain Neurosurgical Center, Lexington, KY, USA.
Pain Physician. 2010 Mar-Apr;13(2):167-86.
Urine drug testing has become a widely used tool in American society for deterring illicit drug use. In the practice of medicine, urine drug testing is commonly used to help diagnose substance misuse, abuse, or addiction.
This narrative review provides an informed perspective on the importance of urine drug testing in the medical treatment of chronic noncancer pain. The history and current uses of urine drug tests in the United States are reviewed, the prevalence and nature of prescription drug misuse is described as is related to chronic noncancer pain, and implications and considerations for practitioners are presented related to the noncancer pain diagnosis and treatment.
Practitioners are confronted with the ethical and legal dilemma of being called to adequately treat chronic pain in a culture with a high prevalence of prescription drug abuse. Yet the symptoms of drug abuse are nonspecific and therefore of limited value to the practitioner in determining patient compliance to drug treatment regimens. In contrast, urine drug testing has a reliable history, both in and out of medicine, as an independent sign of drug misuse. This sign can be used to aid in the diagnosis and treatment of drug misuse and underlying addictions to improve patient outcomes.
Regular urine drug testing should be a part of acute and chronic pain management whether or not the patient has any signs or symptoms of drug misuse.
尿液药物检测已成为美国社会中广泛使用的工具,用于遏制非法药物使用。在医学实践中,尿液药物检测常用于帮助诊断物质滥用、滥用或成瘾。
本叙述性综述提供了一个有关尿液药物检测在慢性非癌症疼痛的医学治疗中的重要性的知情视角。本文回顾了美国尿液药物检测的历史和当前用途,描述了与慢性非癌症疼痛相关的处方药滥用的普遍性和性质,并介绍了与非癌症疼痛诊断和治疗相关的从业者的影响和考虑因素。
从业者面临着在一个普遍存在处方药滥用的文化中,既要充分治疗慢性疼痛,又要面对道德和法律困境。然而,药物滥用的症状是非特异性的,因此对于确定患者对药物治疗方案的依从性,对从业者的价值有限。相比之下,尿液药物检测在医学内外都有着可靠的历史,是药物滥用的独立标志。该标志物可用于辅助药物滥用和潜在成瘾的诊断和治疗,以改善患者的预后。
无论患者是否有任何药物滥用的迹象或症状,定期进行尿液药物检测都应成为急性和慢性疼痛管理的一部分。