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根据欧洲泌尿生殖放射学会(ESUR)指南,在门诊环境中进行现场肌酐测量,对肾功能不全进行筛查。

Screening for renal insufficiency following ESUR (European Society of Urogenital Radiology) guidelines with on-site creatinine measurements in an outpatient setting.

机构信息

IMAMED Radiologie Nordwest, Basel, Switzerland.

出版信息

Eur Radiol. 2010 Aug;20(8):1926-33. doi: 10.1007/s00330-010-1754-2. Epub 2010 Mar 23.

Abstract

OBJECTIVE

To report the results and implications for workflow following introduction of ESUR guidelines to screen for potential renal insufficiency (RI) in private practice with on-site creatinine measurements.

METHODS

A total of 1,766 consecutive outpatients scheduled for contrast-enhanced CT (CECT) completed the ESUR questionnaire enquiring about kidney disease, renal surgery, proteinuria, diabetes mellitus, hypertension, gout or use of nephrotoxic drugs. Patients with positive risk factors underwent on-site creatinine measurement and calculation of estimated glomerular filtration rate (eGFR). Attending radiologists adapted subsequent imaging depending on renal function and presence of risk factors.

RESULTS

One or more ESUR risk factors were present in 796 (45.1%) patients, including hypertension (37.7%), nephrotoxic medication (21.3%), diabetes mellitus (8.0%), proteinuria (3.9%), renal disease (4.1%), gout (3.1%) and renal surgery (2.6%). Pre-procedural creatinine measurements revealed severe RI (eGFR < 30 ml min(-1) 1.73 m(-2)) in 10 (1.3%) and moderate RI (eGFR 30-59 ml min(-1) 1.73 m(-2)) in 106 (13.8%). Imaging work-up was adapted in 132 (16.6%) as follows: reduction of contrast material dose (n = 85), CT without contrast (n = 40), changeover to MRI (n = 3) or scintigraphy (n = 4).

CONCLUSION

Screening for RI following ESUR guidelines requires creatinine measurements in nearly half of outpatients scheduled for CECT and reveals moderate to severe renal impairment in 6.6%.

摘要

目的

报告在私人诊所引入 ESUR 指南以筛查潜在肾功能不全(RI)并进行现场肌酐测量后的工作流程结果及其意义。

方法

共有 1766 名连续的预约接受对比增强 CT(CECT)的门诊患者完成了 ESUR 问卷,询问了肾脏疾病、肾脏手术、蛋白尿、糖尿病、高血压、痛风或使用肾毒性药物等情况。有阳性危险因素的患者进行了现场肌酐测量和估算肾小球滤过率(eGFR)的计算。主治放射科医生根据肾功能和危险因素的存在调整了后续的成像。

结果

796 名(45.1%)患者存在 1 个或多个 ESUR 危险因素,包括高血压(37.7%)、肾毒性药物(21.3%)、糖尿病(8.0%)、蛋白尿(3.9%)、肾脏疾病(4.1%)、痛风(3.1%)和肾脏手术(2.6%)。术前肌酐测量显示严重 RI(eGFR < 30 ml min(-1) 1.73 m(-2))10 例(1.3%),中度 RI(eGFR 30-59 ml min(-1) 1.73 m(-2))106 例(13.8%)。对 132 名患者(16.6%)进行了影像学检查调整,包括减少造影剂剂量(n = 85)、无造影 CT(n = 40)、改用 MRI(n = 3)或闪烁扫描(n = 4)。

结论

按照 ESUR 指南筛查 RI 需对近半数预约 CECT 的门诊患者进行肌酐测量,并显示 6.6%的患者存在中度至重度肾功能不全。

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