Veetil Praveen Kottath, Mukkadan Joseph Kurian
Little Flower Medical Research Centre, Angamaly - 683 572.
Indian J Physiol Pharmacol. 2009 Jul-Sep;53(3):235-42.
Allocentric spatial learning can be assessed using popular spontaneous alternation behaviour (SAB) tested with T-maze, and also using radial arm maze (RAM) tasks. But the SAB testing has been reported to have lack of validity as a measure of retention, especially when used as a measure of short-term memory. A more complex dual alternated task was designed to clarify whether increasing novelty and alternation factors in a task will increase or decrease the short-term and long-term memory in rats. Rats were made to learn both T-maze spontaneous alternation task and RAM task alternatively. Another group of rats were made to learn both the task separately without any alternation. And control group of rats were assigned to learn only one type of task. It was found that the group of rats performing "alternated dual task" could acquire the tasks more easily than the control groups and non alternated dual task groups. This enhancement of acquisition was associated only with the complex task (RAM task) among the dual tasks. More over their retention (memory) ability was very significantly enhanced for both the tasks in dual tasks. It can be concluded that, the principle of "alternated dual task" can be made use when a complex task has to be acquired and learned faster by rats; as alternation with simple task enhances the ability of rats to learn and memorize a complex task more efficiently.
自我中心空间学习可以通过使用T迷宫测试的流行的自发交替行为（SAB）来评估，也可以使用放射状臂迷宫（RAM）任务来评估。但据报道，SAB测试作为一种记忆测量方法缺乏有效性，尤其是在用作短期记忆测量时。设计了一个更复杂的双重交替任务，以阐明在任务中增加新颖性和交替因素是否会增加或减少大鼠的短期和长期记忆。让大鼠交替学习T迷宫自发交替任务和RAM任务。另一组大鼠分别学习这两项任务，不进行任何交替。并将对照组大鼠分配为只学习一种类型的任务。发现执行“交替双重任务”的大鼠组比对照组和非交替双重任务组更容易完成任务。这种获取能力的增强仅与双重任务中的复杂任务（RAM任务）相关。此外，它们对双重任务中两项任务的保持（记忆）能力都有非常显著的提高。可以得出结论，当大鼠必须更快地获取和学习复杂任务时，可以利用“交替双重任务”的原理；因为与简单任务交替可以提高大鼠更有效地学习和记忆复杂任务的能力。
