Department of Gynecology and Obstetrics, Klinikum der Ludwig-Maximilians-Universitaet Muenchen. Maistr. 11, 80337 Munich, Germany.
Psychosomatics. 2010 Mar-Apr;51(2):112-23. doi: 10.1176/appi.psy.51.2.112.
The number of long-term survivors of breast cancer has increased over recent decades because of many treatment advances. Thus, long-term quality of life (QoL) and factors affecting it are of growing research interest.
The authors investigated longitudinal changes in QoL and anxiety in breast cancer patients and differences in QoL and anxiety in various oncological subgroups.
A group of 236 women with a primary diagnosis of breast cancer or carcinoma in-situ completed questionnaires after surgical treatment, 6 months, and 12 months post-surgery.
QoL scores of breast cancer patients improved over time, but impairments in terms of anxiety, body image, and sexual functioning were still observed. Younger patients were more likely to be distressed by cancer diagnosis and treatment.
Surgical modality and tumor prognostic factors, however, seemed to play a minor role in patients' subjective QoL, which is discussed in terms of the "well-being paradox."
由于许多治疗上的进步，近年来乳腺癌的长期幸存者人数有所增加。因此，长期生活质量（QoL）及其影响因素越来越受到研究关注。
作者研究了乳腺癌患者 QoL 和焦虑的纵向变化，以及不同肿瘤亚组之间 QoL 和焦虑的差异。
一组 236 名患有原发性乳腺癌或原位癌的女性在手术后、术后 6 个月和 12 个月完成了问卷调查。
乳腺癌患者的 QoL 评分随时间推移而提高，但焦虑、身体形象和性功能障碍仍存在。年轻患者更有可能因癌症诊断和治疗而感到困扰。
然而，手术方式和肿瘤预后因素似乎对患者的主观 QoL 影响较小，这一点将根据“幸福悖论”进行讨论。
