Hirai Keitaro, Takeyoshi Izumi, Kawate Susumu, Sunose Yutaka, Yoshinari Daisuke, Totsuka Osamu, Ogawa Hiroomi, Kato Yunosuke
Dept. of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine.
Gan To Kagaku Ryoho. 2010 Mar;37(3):517-20.
A 64-year-old female presented with a left cervical tumor. Gastrointestinal endoscopic examination showed advanced gastric cancer type 3, which was diagnosed as poorly-differentiated adenocarcinoma. Computed tomography (CT) showed hugely enlarged Virchow and para-aortic lymph nodes. She was treated with oral S-1, 100 mg/day for 28 days, followed by a 2-week rest. After two courses, S-1 was administered for 14 days followed by a 7-day rest because of side effects. After five courses of treatment, CT showed complete disappearance of the lymph node metastases. Total gastrectomy and lymph node dissection were performed. The histology was judged as Grade 2. The residual cancer in the stomach was only 2mm in size, and there were no viable cancer cells in any lymph nodes. One year postoperatively, the patient is alive without recurrence.
一名64岁女性因左颈部肿瘤就诊。胃肠内镜检查显示为进展期3型胃癌，诊断为低分化腺癌。计算机断层扫描（CT）显示魏尔啸淋巴结和主动脉旁淋巴结肿大明显。给予口服替吉奥，100毫克/天，共28天，随后休息2周。两个疗程后，因出现副作用，替吉奥改为服用14天，休息7天。经过五个疗程的治疗，CT显示淋巴结转移灶完全消失。遂行全胃切除术及淋巴结清扫术。组织学检查判定为2级。胃内残留癌灶大小仅2毫米，且任何淋巴结中均无存活癌细胞。术后一年，患者存活且无复发。
