Uchiyama C, Kondoh H, Shintani H
Cardiovascular Surgery, Otemae Hospital, Osaka, Japan.
Thorac Cardiovasc Surg. 2010 Mar;58(2):115-7. doi: 10.1055/s-2008-1039313. Epub 2010 Mar 23.
We describe the first reported case of acute methemoglobinemia associated with ochronotic valvular heart disease. A 79-year-old man with ochronotic valvular heart disease experienced decreased urinary output starting 9 days after an operation. Thereafter, the patient's methemoglobin concentration acutely increased, indicating systemic cyanosis, while the arterial partial oxygen pressure (PaO (2)) was maintained at around 200 mmHg. In patients with ochronotic valvular heart disease, acute methemoglobinemia may occur, as in cases of renal failure or oliguresis.
我们报告首例与褐黄病性心脏瓣膜病相关的急性高铁血红蛋白血症病例。一名患有褐黄病性心脏瓣膜病的79岁男性在手术后第9天开始出现尿量减少。此后，患者的高铁血红蛋白浓度急剧升高，提示全身性发绀，而动脉血氧分压（PaO₂）维持在200 mmHg左右。在患有褐黄病性心脏瓣膜病的患者中，可能会发生急性高铁血红蛋白血症，如在肾衰竭或少尿的情况下。
