Cardiology Division, VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia 23298-0036, USA.
Catheter Cardiovasc Interv. 2010 Mar 1;75 Suppl 1:S39-42. doi: 10.1002/ccd.22408.
Drug-eluting stents reduce restenosis, particularly in uncomplicated lesions. Despite limited on-label indications, drug-eluting stents have been universally adopted. However, there have been early sporadic reports of stent thrombosis. This article will review the risk factors for stent thrombosis and will briefly discuss recent trials comparing the safety, efficacy, and mortality for bare-metal and drug-eluting stents.
药物洗脱支架可减少再狭窄,特别是在非复杂性病变中。尽管适应证有限,但药物洗脱支架已被普遍采用。然而,早期有零星报道称出现支架血栓。本文将回顾支架血栓形成的危险因素,并简要讨论比较裸金属支架和药物洗脱支架安全性、疗效和死亡率的最新试验。