Division of Cardiology, Washington University, School of Medicine, St. Louis, Missouri 63110, USA.
Catheter Cardiovasc Interv. 2010 Mar 1;75 Suppl 1:S1-6. doi: 10.1002/ccd.22366.
Infarct size may be reduced by left ventricular unloading after ST-segment elevation MI (STEMI) in addition to reperfusion therapy. Likewise, high-risk percutaneous coronary intervention (PCI) may benefit from periprocedural support especially in patients with low cardiac output at baseline or when periprocedural hemodynamic deterioration is anticipated. Traditionally, intraaortic balloon-pumps have been used in acute MI with cardiogenic shock. As this modality has limited hemodynamic benefits, new developments have focused on active hemodynamic assist devices. These devices actively unload the left ventricle increasing cardiac output by 2.5-5 L/min and are increasingly easier to implant and monitor. Thus, interventional cardiologists will be able to offer a safer more effective alternative to an increasing patient population with complex cardiac conditions and high-risk PCI.
梗塞面积可能会缩小左心室卸载后 ST 段抬高心肌梗死 (STEMI) 除了再灌注治疗。同样,高风险经皮冠状动脉介入治疗 (PCI) 可能受益于围手术期的支持,特别是在基础心脏输出量低的患者或预计围手术期血流动力学恶化时。传统上,主动脉内球囊泵已被用于急性心肌梗死伴心源性休克。由于这种方式对血流动力学的益处有限,新的发展重点是积极的血流动力学辅助装置。这些设备主动卸载左心室增加心输出量 2.5-5 L/min,越来越容易植入和监测。因此,介入心脏病专家将能够为越来越多的患有复杂心脏疾病和高风险 PCI 的患者提供更安全、更有效的替代方案。