肝癌的新治疗靶点：Reptin ATP酶与肝癌细胞衰老 - Suppr

Suppr

超能文献

New therapeutic targets in HCC: reptin ATPase and HCC senescence.

作者信息

Berasain Carmen

出版信息

J Hepatol. 2010 May;52(5):633-4. doi: 10.1016/j.jhep.2010.01.020. Epub 2010 Feb 17.

DOI:10.1016/j.jhep.2010.01.020

PMID:20334944

Abstract

摘要

相似文献

New therapeutic targets in HCC: reptin ATPase and HCC senescence.肝癌的新治疗靶点：Reptin ATP酶与肝癌细胞衰老

J Hepatol. 2010 May;52(5):633-4. doi: 10.1016/j.jhep.2010.01.020. Epub 2010 Feb 17.

In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence.体内沉默 Reptin 可阻断异种移植中人肝细胞癌的进展，并与复制性衰老相关。

J Hepatol. 2010 May;52(5):681-9. doi: 10.1016/j.jhep.2009.12.029. Epub 2010 Mar 4.

The ATPase activity of reptin is required for its effects on tumor cell growth and viability in hepatocellular carcinoma.雷普汀的 ATP 酶活性是其影响肝癌肿瘤细胞生长和活力的必要条件。

Mol Cancer Res. 2013 Feb;11(2):133-9. doi: 10.1158/1541-7786.MCR-12-0455. Epub 2012 Dec 10.

Metalloproteinase meprin α regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin.金属蛋白酶meprinα调节人肝癌细胞的迁移和侵袭，是癌蛋白Reptin的介质。

Oncotarget. 2017 Jan 31;8(5):7839-7851. doi: 10.18632/oncotarget.13975.

Sarcomatoid hepatocellular carcinoma: From clinical features to cancer genome.肉瘤样肝细胞癌：从临床特征到癌症基因组。

Cancer Med. 2021 Sep;10(18):6227-6238. doi: 10.1002/cam4.4162. Epub 2021 Jul 31.

Reptin regulates insulin-stimulated Akt phosphorylation in hepatocellular carcinoma via the regulation of SHP-1/PTPN6.Reptin通过调节SHP-1/PTPN6来调控肝细胞癌中胰岛素刺激的Akt磷酸化。

Cell Biochem Funct. 2017 Aug;35(6):289-295. doi: 10.1002/cbf.3274. Epub 2017 Aug 22.

Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells.肝细胞癌衍生细胞中复制性衰老的重编程。

Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2178-83. doi: 10.1073/pnas.0510877103. Epub 2006 Feb 6.

Aspartate β-hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinoma.天冬氨酸β-羟化酶通过糖原合酶激酶3β调节肝癌细胞衰老。

Hepatology. 2016 Apr;63(4):1213-26. doi: 10.1002/hep.28411. Epub 2016 Feb 19.

CHD5 a tumour suppressor is epigenetically silenced in hepatocellular carcinoma.肿瘤抑制因子CHD5在肝细胞癌中发生表观遗传沉默。

Liver Int. 2014 Jul;34(6):e151-60. doi: 10.1111/liv.12503. Epub 2014 Mar 15.

Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism.三磷酸腺苷酶蓬亭在肝细胞癌中过表达，并通过一种新的翻译后机制与瑞亭共同调控。

Hepatology. 2009 Dec;50(6):1871-83. doi: 10.1002/hep.23215.

引用本文的文献

Mitochondrial-Related Transcriptome Feature Correlates with Prognosis, Vascular Invasion, Tumor Microenvironment, and Treatment Response in Hepatocellular Carcinoma.线粒体相关转录组特征与肝细胞癌的预后、血管侵犯、肿瘤微环境和治疗反应相关。

Oxid Med Cell Longev. 2022 Apr 30;2022:1592905. doi: 10.1155/2022/1592905. eCollection 2022.

The Role of Pontin and Reptin in Cellular Physiology and Cancer Etiology.Pontin和Reptin在细胞生理学及癌症病因学中的作用

Front Mol Biosci. 2017 Aug 24;4:58. doi: 10.3389/fmolb.2017.00058. eCollection 2017.

Cytoplasmic expression of pontin in renal cell carcinoma correlates with tumor invasion, metastasis and patients' survival.Pontin在肾细胞癌中的细胞质表达与肿瘤侵袭、转移及患者生存率相关。

PLoS One. 2015 Mar 9;10(3):e0118659. doi: 10.1371/journal.pone.0118659. eCollection 2015.

Identification of biomarkers for esophageal squamous cell carcinoma using feature selection and decision tree methods.使用特征选择和决策树方法鉴定食管鳞状细胞癌的生物标志物。

ScientificWorldJournal. 2013 Dec 12;2013:782031. doi: 10.1155/2013/782031. eCollection 2013.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验