[臭氧水对感染伤口炎症及修复的影响]

[Effect of ozone water on the inflammation and repair in infected wounds].

作者信息

Huang Hua-jun, Yu Bin, Lin Qing-rong, Wang Bo-wei, Chen Hui-qiang

机构信息

Department Orthopedic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2010 Mar;30(3):515-8.

PMID:20335124

Abstract

OBJECTIVE

To study the effect of ozone water in promoting the healing of infected wounds.

METHODS

Fifty Wistar rats were randomly divided into 5 groups, namely chlorhexidine treatment group, 5, 10, and 20 mg/L ozone water treatment groups, and the control group without any treatment. Infected wounds were induced on the back of the rats, and at 48 h of infection, chlorhexidine or ozone water was applied once daily for 9 days. Before and at days 3, 6, and 9 of the treatment, the wound changes were observed. The WBC in the tail venous blood was detected and the incised skin and muscular tissues were pathologically examined. RESULTS AMD CONCLUSION: Ozone water showed better effects in promoting the healing of the infected wound, especially at higher doses of 10 and 20 mg/L.

摘要

目的

研究臭氧水对感染伤口愈合的促进作用。

方法

将50只Wistar大鼠随机分为5组，即洗必泰治疗组、5、10和20mg/L臭氧水处理组，以及未作任何处理的对照组。在大鼠背部制造感染伤口，感染48小时后，每天涂抹一次洗必泰或臭氧水，持续9天。在治疗前以及治疗第3、6和9天观察伤口变化。检测尾静脉血中的白细胞，并对切开的皮肤和肌肉组织进行病理检查。结果与结论：臭氧水在促进感染伤口愈合方面显示出更好的效果，尤其是在10和20mg/L的较高剂量下。