[不同细胞培养物中γ-氨基丁酸（GABA）水平分化的影响]
[Effect of differentiation of GABA levels in various cell cultures].
作者信息
Simler S, Gensburger C, Ciesielski L, Mandel P
出版信息
C R Seances Soc Biol Fil. 1977;171(5):1116-21.
PMID:203373
Abstract
The effect of factors inducing somatic differentiation on cellular GABA level has been investigated. C6 glial cells from a rat astrocytoma present a significantly higher GABA level than the other glial or neuronal cells studied. A significant decrease in GABA levels in most cases parallels the somatic differentiation induced either by withdrawal of fetal serum, or by addition of dibutyryl cyclic AMP to the culture medium.
摘要
研究了诱导体细胞分化的因素对细胞γ-氨基丁酸（GABA）水平的影响。来自大鼠星形细胞瘤的C6神经胶质细胞的GABA水平显著高于所研究的其他神经胶质细胞或神经元细胞。在大多数情况下，GABA水平的显著降低与因去除胎牛血清或向培养基中添加二丁酰环磷腺苷诱导的体细胞分化同时发生。
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