Green Lane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Grafton, Auckland, New Zealand.
Ann Thorac Surg. 2010 Apr;89(4):1244-9. doi: 10.1016/j.athoracsur.2009.12.035.
A midterm retrospective analysis of the transaortic primary suture repair of perimembranous or conal ventricular septal defects with aortic valve prolapse was conducted.
From January 1998 to January 2006, 56 patients underwent transaortic repair of perimembranous or conal ventricular septal defects using the direct suture technique. The mean age at operation was 7.7+/-5.0 years (37 males). Twenty-eight patients had none or trivial aortic regurgitation (AR), 19 had mild AR, and 9 had moderate or severe AR. The mean defect size was 7.0+/-2.6 mm at operation.
There was no early mortality. In the immediate postoperative period, AR remained unchanged in 32 patients, improved in 17, and worsened in 9, including 2 patients who required early reoperation. Median follow-up was 3 years (range, 2 months to 8 years). There was 1 late death. Aortic regurgitation had deteriorated in 21 patients, 3 of whom required late reoperation, and improved in 5 compared with the preoperative state. Freedom from deterioration in AR was 97% at 2 years and 71% at 4 years. Deterioration in aortic valve function was independent of demographic and morphologic features.
This surgical technique does not prevent progressive aortic valve dysfunction, which may be related to structural deficiency of the valve leaflet or distortion of the annulus by direct suture closure of the ventricular septal defect. Early closure may prevent structural leaflet damage, whereas adaptation of the transaortic technique to include a shallow ventricular septal defect patch may be beneficial in older patients.
对主动脉瓣脱垂合并膜周部或圆锥部室间隔缺损的经主动脉直接缝合修复进行了中期回顾性分析。
1998 年 1 月至 2006 年 1 月,56 例行经主动脉修复膜周部或圆锥部室间隔缺损,采用直接缝合技术。手术时平均年龄为 7.7+/-5.0 岁(37 例男性)。28 例无或轻度主动脉瓣反流(AR),19 例轻度 AR,9 例中度或重度 AR。手术时平均缺损大小为 7.0+/-2.6mm。
无早期死亡。术后即刻 AR 无变化 32 例,改善 17 例,恶化 9 例,其中 2 例需早期再次手术。中位随访 3 年(2 个月至 8 年)。有 1 例晚期死亡。21 例 AR 恶化,其中 3 例需晚期再次手术,5 例与术前比较改善。2 年 AR 无恶化率为 97%,4 年为 71%。主动脉瓣功能恶化与人口统计学和形态特征无关。
这种手术技术不能防止进行性主动脉瓣功能障碍,这可能与瓣叶的结构缺陷或直接缝合室间隔缺损关闭时环的变形有关。早期关闭可能防止结构瓣叶损伤,而将经主动脉技术适应包括一个浅的室间隔缺损补片可能对老年患者有益。