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超声引导下髋关节骨关节炎的类固醇注射:疗效。

Steroid injection for hip osteoarthritis: efficacy under ultrasound guidance.

机构信息

Rheumatology Division, County Hospital Turda, Turda, Romania.

出版信息

Rheumatology (Oxford). 2010 Aug;49(8):1490-4. doi: 10.1093/rheumatology/keq030. Epub 2010 Mar 24.

Abstract

OBJECTIVE

To determine the efficacy of IA corticosteroid (CS) injection in pain reduction for hip OA under ultrasound (US) guidance.

METHODS

Forty patients [mean age 62.78 (8.16) years] fulfilling ACR criteria for hip OA, with synovitis detected at US, gave their consent for IA US-guided CS injection because of pain refractory to conventional therapy. At baseline, at 1 and 3 months, patients filled up a visual analogue scale (VAS) pain on walking, performed the Lequesne index and were checked by US for synovitis. Results were compared with age-matched controls. The occurrence of side effects both short and long term was monitored.

RESULTS

IA steroid deposition was performed under US guidance. After 1 and 3 months, walking pain VAS was significantly reduced vs baseline (P < 0.001) and had high correlation with Lequesne index. Synovial hypertrophy was reduced in 75% of the hips after 1 and 3 months vs baseline (P < 0.001). In the group of controls, hip walking pain VAS, Lequesne index and synovial hypertrophy were not changed at 3 months vs baseline (P > 0.05). Transient facial rash was present in 16 patients during the first 24-48 h after injection. No side effects were reported.

CONCLUSION

US-guided steroid injections in hip OA is an efficacious and safe therapeutic approach to achieve pain control and reduction of synovial hypertrophy avoiding the use of X-ray-guided procedure.

摘要

目的

确定在超声 (US) 引导下关节内皮质类固醇 (CS) 注射治疗髋关节炎疼痛的疗效。

方法

40 名符合髋关节炎 ACR 标准的患者 [平均年龄 62.78(8.16)岁],US 检查发现滑膜炎,由于对常规治疗的疼痛反应不佳,同意接受 US 引导下 IA CS 注射。在基线、1 个月和 3 个月时,患者使用视觉模拟量表 (VAS) 评估行走时的疼痛、进行 Lequesne 指数评估,并通过 US 检查滑膜炎。将结果与年龄匹配的对照组进行比较。监测短期和长期的副作用发生情况。

结果

在 US 引导下进行关节内类固醇沉积。治疗 1 个月和 3 个月后,行走疼痛 VAS 与基线相比明显降低 (P < 0.001),与 Lequesne 指数具有高度相关性。1 个月和 3 个月后,75%的髋关节滑膜炎增生得到缓解 (P < 0.001)。在对照组中,3 个月时髋关节行走疼痛 VAS、Lequesne 指数和滑膜炎增生与基线相比无变化 (P > 0.05)。注射后 24-48 小时内,16 名患者出现短暂的面部皮疹。未报告任何副作用。

结论

在 US 引导下进行髋关节炎的皮质类固醇注射是一种有效且安全的治疗方法,可以控制疼痛并减少滑膜炎增生,避免使用 X 射线引导的程序。

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