Suppr超能文献

在透视引导下经外侧入路关节腔内注射透明质酸治疗晚期髋骨关节炎的疗效

Efficacy of intraarticular hyaluronic acid injection through a lateral approach under fluoroscopic control for advanced hip osteoarthritis.

作者信息

Eyigör Can, Pirim Alihan, Eyigör Sibel, Uyar Meltem

机构信息

Department of Anesthesiology and Reanimation, Ege University Faculty of Medicine, İzmir, Turkey.

出版信息

Agri. 2010 Oct;22(4):139-44.

Abstract

OBJECTIVES

Hyaluronic acid (HA) is used for intraarticular treatment of hip osteoarthritis (OA). The objective of this study was to determine the efficacy of intraarticular injection of HA through a lateral approach under fluoroscopic control for advanced hip OA.

METHODS

The study included 21 patients with advanced hip OA. All patients received 2.5 ml HA injection once a week for 3 weeks by lateral approach under fluoroscopic control. Disability (Lequesne index), pain scores (visual analog scale-VAS) and analgesic use of patients were assessed before treatment and 1, 3 and 6 months after the treatment.

RESULTS

Lequesne index and VAS pain scores measured 1, 3 and 6 months after treatment were significantly lower compared to baseline scores (p<0.001). Although analgesic use was significantly reduced 1 and 3 months after treatment compared to baseline (p<0.05), no difference was determined in analgesic use at the 6th month (p>0.05). No side effect was observed.

CONCLUSION

In conclusion, intraarticular HA injection through a lateral approach under fluoroscopic control was shown to be a safe and effective method for patients with advanced hip OA.

摘要

目的

透明质酸(HA)用于髋关节骨关节炎(OA)的关节腔内治疗。本研究的目的是确定在透视控制下经外侧入路关节腔内注射HA治疗晚期髋关节OA的疗效。

方法

本研究纳入21例晚期髋关节OA患者。所有患者在透视控制下经外侧入路每周注射1次2.5ml HA,共注射3周。在治疗前以及治疗后1、3和6个月评估患者的功能障碍(Lequesne指数)、疼痛评分(视觉模拟量表-VAS)和镇痛药物使用情况。

结果

治疗后1、3和6个月测得的Lequesne指数和VAS疼痛评分与基线评分相比显著降低(p<0.001)。虽然治疗后1和3个月与基线相比镇痛药物使用显著减少(p<0.05),但在第6个月时镇痛药物使用情况无差异(p>0.05)。未观察到副作用。

结论

总之,在透视控制下经外侧入路关节腔内注射HA对晚期髋关节OA患者是一种安全有效的方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验