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保留幽门的胰十二指肠切除术治疗壶腹周围癌,是一种好的选择吗?

Pylorus preserving pancreaticoduodenectomy for peri-ampullary carcinoma, is it a good option?

机构信息

Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Saudi J Gastroenterol. 2010 Apr-Jun;16(2):75-8. doi: 10.4103/1319-3767.61231.

DOI:10.4103/1319-3767.61231
PMID:20339174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3016509/
Abstract

Pancreaticoduodenectomy (PD) is the standard surgical treatment for resectable peri-ampullary tumors. It can be performed with or without pylorus preservation. Many surgeons have a negative opinion of pylorus preserving PD (PPPD) and consider it an inferior operation, especially from an oncological point of view. This article reviews the various aspects of PD in the context of operative factors like blood loss and operation time, complications such as delayed gastric emptying and anastomotic leaks, and the impact on quality of life and survival. We aim to show that PPPD is at least as good as classic PD, if not better in some aspects.

摘要

胰十二指肠切除术(PD)是可切除的壶腹周围肿瘤的标准手术治疗方法。它可以在保留或不保留幽门的情况下进行。许多外科医生对保留幽门的胰十二指肠切除术(PPPD)持否定态度,认为它是一种劣等手术,尤其是从肿瘤学的角度来看。本文综述了 PD 在手术因素(如出血量和手术时间)、并发症(如胃排空延迟和吻合口漏)以及对生活质量和生存的影响等方面的各种情况。我们旨在表明,PPPD 至少与经典 PD 一样好,如果在某些方面更好的话。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8675/3016509/83fad9a41fcc/SJG-16-75-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8675/3016509/83fad9a41fcc/SJG-16-75-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8675/3016509/83fad9a41fcc/SJG-16-75-g001.jpg

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Pylorus preserving pancreaticoduodenectomy for peri-ampullary carcinoma, is it a good option?保留幽门的胰十二指肠切除术治疗壶腹周围癌,是一种好的选择吗?
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引用本文的文献

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Oncol Lett. 2018 May;15(5):6368-6376. doi: 10.3892/ol.2018.8156. Epub 2018 Mar 2.
2
Pylorus preserving pancreaticoduodenectomy.保留幽门的胰十二指肠切除术
Saudi J Gastroenterol. 2010 Apr-Jun;16(2):65. doi: 10.4103/1319-3767.61229.

本文引用的文献

1
Observations on radical surgery for lesions of the pancreas.胰腺病变根治性手术的观察
Surg Gynecol Obstet. 1946 Jun;82:623-31.
2
Standard whipple's operation versus pylorus preserving pancreaticoduodenectomy: a randomized controlled trial study.标准惠普尔手术与保留幽门的胰十二指肠切除术:一项随机对照试验研究。
J Med Assoc Thai. 2008 May;91(5):693-8.
3
Delayed gastric emptying: the state of the highest level of evidence.胃排空延迟:证据级别最高的状态。
J Hepatobiliary Pancreat Surg. 2008;15(3):262-9. doi: 10.1007/s00534-007-1304-8. Epub 2008 Jun 6.
4
A comparison of pancreaticoduodenectomy with pylorus preserving pancreaticoduodenectomy: a meta-analysis of 2822 patients.胰十二指肠切除术与保留幽门的胰十二指肠切除术的比较:对2822例患者的荟萃分析
Eur J Surg Oncol. 2008 Nov;34(11):1237-45. doi: 10.1016/j.ejso.2007.12.004. Epub 2008 Feb 1.
5
Impaired emptying of the retained distal stomach causes delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy.保留远端胃排空功能受损导致保留幽门的胰十二指肠切除术后胃排空延迟。
World J Surg. 2007 Aug;31(8):1606-15. doi: 10.1007/s00268-007-9100-9.
6
The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer.幽门:保留还是舍弃?保留幽门与标准胰十二指肠切除术治疗胰腺癌或壶腹周围癌的系统评价和荟萃分析
Ann Surg Oncol. 2007 Jun;14(6):1825-34. doi: 10.1245/s10434-006-9330-3. Epub 2007 Mar 8.
7
Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer.保留幽门与经典胰十二指肠切除术治疗胰腺癌的早期及长期营养和功能结果
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Effects of somatostatin prophylaxis after pylorus-preserving pancreaticoduodenectomy: increased delayed gastric emptying and reduced plasma motilin.保留幽门的胰十二指肠切除术后生长抑素预防的效果:胃排空延迟增加及血浆胃动素减少。
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Reconsideration of delayed gastric emptying in pancreaticoduodenectomy.胰十二指肠切除术中延迟胃排空的再思考
World J Surg. 2005 Jul;29(7):873-9; discussion 880. doi: 10.1007/s00268-005-7473-1.
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Complications with reconstruction procedures in pylorus-preserving pancreaticoduodenectomy.保留幽门的胰十二指肠切除术重建手术的并发症
World J Surg. 2005 Jul;29(7):881-4. doi: 10.1007/s00268-005-7697-0.