甲状腺手术后临床和实验室低钙血症的前瞻性研究。
Prospective study of clinical and laboratorial hypocalcemia after thyroid surgery.
机构信息
Hospital Heliópolis, São Paulo, Brazil.
出版信息
Braz J Otorhinolaryngol. 2010 Jan-Feb;76(1):71-7. doi: 10.1590/S1808-86942010000100012.
UNLABELLED
Hypocalcemia can be detected clinically and through lab tests after thyroidectomy.
AIM
To analyze the incidence and risk factors of clinical and laboratorial hypocalcemia after thyroid surgery.
METHODS
Prospective study of 91 patients undergoing thyroidectomy. Demographics, intraoperative, and pathological aspects were correlated to our hypocalcemia findings.
RESULTS
Age higher than 50 (p = 0.022) and complete thyroidectomy (p < 0.001) were considered risk factors for hypoparathyroidism. Complete thyroidectomy was considered a risk factor for the 48-hour laboratorial hypoparathyroidism (p = 0.004). There was no risk factor associated with the one-month laboratorial hypoparathyroidism. There was significance between the 48-hour and the one-month laboratorial hypoparathyroidism.
CONCLUSIONS
Thyroidectomy extension is a risk factor for both the clinical and laboratorial hypoparathyroidism, whereas age is a risk factor for clinical hypoparathyroidism. The detection of 48-hour laboratorial hypoparathyroidism is a predisposing factor for the one-month laboratorial hypoparathyroidism. However, most of the cases were temporary.
未加标签
甲状腺手术后可通过临床和实验室检查发现低钙血症。
目的
分析甲状腺手术后临床和实验室低钙血症的发生率及危险因素。
方法
前瞻性研究 91 例甲状腺切除术患者。将患者的人口统计学、术中及病理方面与低钙血症发现相关联。
结果
年龄大于 50 岁（p=0.022）和全甲状腺切除术（p＜0.001）被认为是甲状旁腺功能减退的危险因素。全甲状腺切除术被认为是术后 48 小时实验室甲状旁腺功能减退的危险因素（p=0.004）。没有与术后 1 个月实验室甲状旁腺功能减退相关的危险因素。术后 48 小时和 1 个月实验室甲状旁腺功能减退之间存在差异。
结论
甲状腺切除术范围是临床和实验室甲状旁腺功能减退的危险因素，而年龄是临床甲状旁腺功能减退的危险因素。术后 48 小时实验室甲状旁腺功能减退是术后 1 个月实验室甲状旁腺功能减退的一个潜在因素。然而，大多数病例是暂时的。
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