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成人原发性甲状旁腺功能减退症:一种罕见的表现。

Adult primary hypoparathyroidism: A rare presentation.

作者信息

Chakrabarty Ashima Datey

机构信息

Department of Pulmonology, Eesha Multispeciality Hospitals, Hyderabad, India.

出版信息

Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S201-2. doi: 10.4103/2230-8210.119571.

DOI:10.4103/2230-8210.119571
PMID:24251158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3830304/
Abstract

The common causes of stridor in adults are abscesses or swelling of upper airway, tumors, paralysis or malfunction of vocal cords. Laryngospasm due to hypocalcemia is a rare cause of stridor in adults, although occasionally reported in the neonates. We report an elderly lady having stridor and laryngospasm, secondary to acquired hypoparathyroidism and secondary hypocalcemia, without risk factors for hypoparathyroidism such as recent neck surgery or irradiation. We did an extensive review of literature to find only a few cases of acquired primary hypoparathyroidism in adults with the only complaint being stridor. This case underlines the fact that a common symptom like stridor rarely occurs due to uncommon causes. This case is being reported for its rarity and amenability to complete cure in event of correct diagnosis.

摘要

成人喘鸣的常见原因是上呼吸道脓肿或肿胀、肿瘤、声带麻痹或功能障碍。低钙血症引起的喉痉挛是成人喘鸣的罕见原因,尽管在新生儿中偶尔有报道。我们报告了一位老年女性,继发于获得性甲状旁腺功能减退和继发性低钙血症,出现喘鸣和喉痉挛,且没有甲状旁腺功能减退的危险因素,如近期颈部手术或放疗。我们广泛查阅文献,仅发现少数成人获得性原发性甲状旁腺功能减退病例,唯一的主诉是喘鸣。该病例强调了这样一个事实,即像喘鸣这样的常见症状很少由不常见的原因引起。报告该病例是因其罕见性以及在正确诊断的情况下可完全治愈。

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Adult primary hypoparathyroidism: A rare presentation.成人原发性甲状旁腺功能减退症:一种罕见的表现。
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本文引用的文献

1
Prospective study of clinical and laboratorial hypocalcemia after thyroid surgery.甲状腺手术后临床和实验室低钙血症的前瞻性研究。
Braz J Otorhinolaryngol. 2010 Jan-Feb;76(1):71-7. doi: 10.1590/S1808-86942010000100012.
2
Stridor secondary to hypocalcemia in the elderly: an unusual presentation.老年人低钙血症继发喘鸣:一种不寻常的表现。
Eur J Intern Med. 2008 May;19(3):219-20. doi: 10.1016/j.ejim.2007.04.020. Epub 2007 Sep 19.
3
Hypomagnesaemia associated with diabetes mellitus may cause laryngospasm.与糖尿病相关的低镁血症可能会导致喉痉挛。
Acta Anaesthesiol Scand. 2006 Apr;50(4):512-3. doi: 10.1111/j.1399-6576.2006.00985.x.
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[Laryngospasm: unusual manifestation of celiac disease].[喉痉挛:乳糜泻的不寻常表现]
Schweiz Med Wochenschr. 1993 Mar 13;123(10):432-4.
5
Laryngospasm in hypoparathyroidism.甲状旁腺功能减退症中的喉痉挛
J Laryngol Otol. 1974 Apr;88(4):369-73. doi: 10.1017/s0022215100078804.
6
Hypocalcaemic stridor in children. How often is it missed?儿童低钙性喘鸣。漏诊的频率有多高?
Clin Pediatr (Phila). 1991 Jan;30(1):51-2. doi: 10.1177/000992289103000108.