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神经松解术联合神经周围皮质类固醇注射治疗麻风性神经炎

Treatment of leprous neuritis by neurolysis combined with perineural corticosteroid injection.

作者信息

Dandapat M C, Sahu D M, Mukherjee L M, Panda C, Baliarsing A S

机构信息

Department of Surgery, MKCG Medical College, Orissa, India.

出版信息

Lepr Rev. 1991 Mar;62(1):27-34. doi: 10.5935/0305-7518.19910004.

Abstract

A study on leprous neuritis, involving the ulnar nerve, was carried out on 39 patients. The evaluation of nerve function was done before and after treatment by a score chart. Patients were divided into two groups. Group A (21 patients) was subjected to neurolysis only, and group B (18 patients) were given the combined treatment of neurolysis and perineural corticosteroid injection at the same time as neurolysis and subsequently at the end of the second and third weeks. In group B, 83.3% of patients showed 10% or more increase in the posttreatment score in comparison with 57.1% in group A. Improvement was more marked in paucibacillary cases and when the duration of nerve involvement was less than 3 months. Patients with short segments of nerve involvement with minimal thickening had better recovery. This procedure was observed to be simple, easy and well accepted by the patients, with a marked beneficial effect.

摘要

对39例累及尺神经的麻风性神经炎患者进行了一项研究。治疗前后通过评分表对神经功能进行评估。患者分为两组。A组(21例患者)仅接受神经松解术,B组(18例患者)在进行神经松解术的同时接受神经松解术和神经周围皮质类固醇注射的联合治疗,随后在第二周和第三周结束时进行注射。在B组中,83.3%的患者治疗后评分比治疗前增加了10%或更多,而A组为57.1%。少菌型病例以及神经受累时间少于3个月时改善更为明显。神经受累节段短且增厚轻微的患者恢复较好。观察到该方法简单、易行,患者易于接受,且有显著的有益效果。

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