Suppr超能文献

[多囊肾病的最新见解]

[Recent insights into polycystic kidney disease].

作者信息

Bonny Olivier, Chehade Hassib, Fellmann Florence, Qanadli Salah Dine, Barbey Frédéric

机构信息

Service de néphrologie, Département de médecine, CHUV, Lausanne.

出版信息

Rev Med Suisse. 2010 Mar 3;6(238):454-9.

Abstract

Autosomal dominant polycystic kidney disease is one of the most prevalent genetic diseases and every general practitioner may have to counsel these patients. The follow-up of the patients carrying the trait has changed substantially lately and new treatments have been developed and are close to get approval. We review here the new ultrasound diagnostic criteria, the place of the renal volumetry by MRI in the follow-up, the place of the genetic molecular diagnosis and we discuss the pathogenesis and the future treatment that are in phase III clinical studies and will soon change completely the outcome of the disease.

摘要

常染色体显性多囊肾病是最常见的遗传病之一,每位全科医生都可能需要为这些患者提供咨询。携带该特征患者的随访情况最近有了很大变化,并且已经开发出了新的治疗方法,且即将获得批准。我们在此回顾新的超声诊断标准、MRI肾脏容积测量在随访中的地位、基因分子诊断的地位,并讨论处于III期临床研究且将很快彻底改变该病预后的发病机制和未来治疗方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验