Department of Urology, Cleveland Clinic, OH, USA.
BJU Int. 2010 May;105(9):1296-300. doi: 10.1111/j.1464-410X.2009.09106.x. Epub 2010 Mar 15.
To present our experience with single-port transvesical enucleation of the prostate (STEP) in 34 patients with large-volume benign prostatic hyperplasia (BPH).
We performed STEP in 34 patients with large volume (>60 g) BPH (mean age 69 years, body mass index 26 kg/m(2), and American Society of Anesthesiology class 2). The mean prostate volume estimated by transrectal ultrasonography was 102.5 mL and the mean baseline prostate-specific antigen level was 6.7 ng/mL. A novel single-port device was inserted percutaneously into the bladder through a 2-3 cm incision in the suprapubic skin crease. After establishing pneumovesicum, the prostate adenoma was enucleated transvesically using standard laparoscopic instruments, and the adenoma was extracted in pieces through the port. Digital assistance expedited enucleation of the apical adenoma in 19 (55%) cases.
Transvesical enucleation was completed in all 34 cases; the mean operative duration was 116 min, and the estimated blood loss was 460 mL. There was one death from postoperative bleeding from uncontrolled coagulopathy in a Jehovah's Witness who refused a transfusion of blood and blood products. There were three complications during STEP (one death, one bowel injury and one haemorrhage) and five afterwards (four bleeding, one epididymo-orchitis). Open conversion was necessary in two patients for complications, and extension of the skin incision by 1-2 cm was necessary in two to expedite apical digital enucleation. The mean hospital stay was 3 days and mean analogue pain score at discharge was 2. All 33 patients (excluding the patient who died) were voiding spontaneously at a maximum follow-up of 8 months, with a mean American Urologic Association symptom score of 3, a maximum urinary flow rate of 44 mL/s, and a postvoid residual of 30 mL at the latest follow-up. No patient developed urinary incontinence.
STEP is an effective treatment option for selected patients with large-volume obstructive BPH. Under pneumovesicum using laparoscopic visualization, the entire adenoma can be effectively enucleated and expeditiously extracted through the novel single port. Comparison of the STEP procedure with other open and transurethral techniques will determine its place in the surgical treatment of large-volume BPH.
介绍我们在 34 例大体积良性前列腺增生(BPH)患者中应用经膀胱单孔前列腺切除术(STEP)的经验。
我们对 34 例大体积(>60 g)BPH 患者(平均年龄 69 岁,体重指数 26 kg/m2,美国麻醉医师协会 2 级)进行了 STEP。经直肠超声估计前列腺平均体积为 102.5 mL,前列腺特异性抗原基线水平平均为 6.7 ng/mL。通过耻骨上皮肤皱褶处的 2-3 cm 切口经皮插入新型单孔装置。建立气膀胱后,使用标准腹腔镜器械经膀胱切除前列腺腺瘤,通过端口将腺瘤分块取出。数字辅助在 19 例(55%)病例中加速了顶部腺瘤的切除。
34 例均完成经膀胱前列腺切除术;平均手术时间为 116 分钟,估计失血量为 460 mL。1 例因拒绝输血和血制品的 Jehovah's Witness 术后出血性凝血功能障碍而死亡。在 STEP 期间有 3 例并发症(1 例死亡、1 例肠损伤和 1 例出血)和 5 例术后并发症(4 例出血、1 例附睾炎)。2 例因并发症需要转为开放手术,2 例需要延长皮肤切口 1-2 cm 以加速顶部数字化切除。平均住院时间为 3 天,出院时平均模拟疼痛评分 2 分。33 例患者(死亡患者除外)在最长 8 个月的随访时均能自主排尿,平均美国泌尿外科学会症状评分 3 分,最大尿流率 44 mL/s,最晚随访时残余尿量 30 mL。无患者发生尿失禁。
STEP 是治疗大体积梗阻性 BPH 患者的有效选择。在气膀胱下使用腹腔镜可视化,整个腺瘤可以有效地被切除,并通过新型单孔迅速取出。将 STEP 手术与其他开放和经尿道技术进行比较,将确定其在大体积 BPH 手术治疗中的地位。