Griffin J W, Tooms R E, Mendius R A, Clifft J K, Vander Zwaag R, el-Zeky F
Department of Rehabilitation Sciences, College of Allied Health Sciences, University of Tennessee, Memphis 38163.
Phys Ther. 1991 Jun;71(6):433-42; discussion 442-4. doi: 10.1093/ptj/71.6.433.
The purpose of this study was to assess the efficacy of high voltage pulsed direct current (HVPC) for healing of pressure ulcers in patients with spinal cord injury. Seventeen patients having pressure ulcers in the pelvic region were randomly assigned to either an HVPC group or a placebo HVPC group. Treatments were given for 1 hour a day for 20 consecutive days. The HVPC protocol consisted of an aluminum-foil electrode placed over the ulcer and set at negative polarity in reference to the dispersive electrode placed on the thigh. Stimulator frequency was set at 100 pps, and an intensity of 200 V was used. Measurements of ulcer surface area were conducted before treatment and after treatment days 5, 10, 15, and 20. To measure ulcer area (in square millimeters), slides taken at each measurement time were projected at actual size, traced, and digitized. Percentage of change compared with pretreatment ulcer size was calculated for each measurement time. Ulcers in the HVPC group demonstrated significantly greater percentage-of-change decreases from their pretreatment size than did ulcers in the placebo group at days 5, 15, and 20. The results suggest that HVPC, in conjunction with good nursing care, can significantly increase the healing rate of pelvic ulcers in patients with spinal cord injury.
本研究的目的是评估高压脉冲直流电(HVPC)对脊髓损伤患者压疮愈合的疗效。17例骨盆区域有压疮的患者被随机分为HVPC组或安慰剂HVPC组。连续20天每天治疗1小时。HVPC方案包括将铝箔电极置于溃疡上方,并相对于置于大腿的分散电极设置为负极性。刺激器频率设置为100次/秒,使用200V的强度。在治疗前以及治疗第5、10、15和20天后测量溃疡表面积。为了测量溃疡面积(以平方毫米为单位),将每次测量时拍摄的载玻片按实际尺寸投影、描绘并数字化。计算每个测量时间与治疗前溃疡大小相比的变化百分比。在第5、15和20天,HVPC组的溃疡与治疗前大小相比的变化百分比下降幅度明显大于安慰剂组。结果表明,HVPC与良好的护理相结合,可显著提高脊髓损伤患者骨盆溃疡的愈合率。