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用整块全厚皮片进行着色性干皮病的面部皮肤重建。

Facial resurfacing in xeroderma pigmentosum with monoblock full-thickness skin graft.

作者信息

Atabay K, Celebi C, Cenetoglu S, Baran N K, Kiymaz Z

机构信息

Department of Plastic and Reconstructive Surgery, Gazi University School of Medicine, Ankara, Turkey.

出版信息

Plast Reconstr Surg. 1991 Jun;87(6):1121-5. doi: 10.1097/00006534-199106000-00018.

DOI:10.1097/00006534-199106000-00018
PMID:2034733
Abstract

A case of xeroderma pigmentosum with multiple skin tumors on the face that was treated with total excision and replacement of face skin except the eyelids with a monoblock full-thickness abdominal skin graft is reported. The quality and tumor-free features of the monoblock full-thickness skin graft in xeroderma pigmentosum are indicated. Despite the increased morbidity of the donor region, the radical surgical approach advocated here has improved the prognosis in the case reported.

摘要

报告了一例面部患有多发性皮肤肿瘤的着色性干皮病患者,除眼睑外,采用整块全厚腹部皮肤移植对其面部皮肤进行了全切除并置换。文中指出了整块全厚皮肤移植用于着色性干皮病时的质量和无瘤特性。尽管供区发病率有所增加,但本文所倡导的根治性手术方法改善了所报告病例的预后。

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引用本文的文献

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Technical Aspects and Difficulties in the Management of Head and Neck Cutaneous Malignancies in Xeroderma Pigmentosum.着色性干皮病患者头颈部皮肤恶性肿瘤管理中的技术要点与难点
Arch Plast Surg. 2016 Jul;43(4):344-51. doi: 10.5999/aps.2016.43.4.344. Epub 2016 Jul 20.
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Preclinical corrective gene transfer in xeroderma pigmentosum human skin stem cells.原发性色素干皮病患者皮肤干细胞的临床前矫正基因转移。
Mol Ther. 2012 Apr;20(4):798-807. doi: 10.1038/mt.2011.233. Epub 2011 Nov 8.
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Monoblock Expanded Full-thickness Graft for Resurfacing of the Burned Face in Young Patients.
用于年轻患者烧伤面部修复的整体式扩展全厚皮移植术
Ann Burns Fire Disasters. 2007 Dec 31;20(4):176-80.
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Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice.皮肤细胞中的基因转导:预防着色性干皮病小鼠患癌
Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17759-64. doi: 10.1073/pnas.0406304101. Epub 2004 Dec 14.