美沙酮在培养的哺乳动物细胞中的代谢。
The metabolism of methadone by cultured mammalian cells.
作者信息
Will P C, Noteboom W D
出版信息
Experientia. 1978 Feb 15;34(2):217-9. doi: 10.1007/BF01944687.
PMID:203475
Abstract
Rat hepatoma tissue culture cells and mouse leukemic cells were found to metabolize [1-3H] methadone to at least 2 unidentified radioactive compounds. These results suggest that cultured cells may be useful models for studying methadone metabolism by specific cell types.
摘要
已发现大鼠肝癌组织培养细胞和小鼠白血病细胞可将[1-³H]美沙酮代谢为至少2种未鉴定的放射性化合物。这些结果表明，培养细胞可能是研究特定细胞类型对美沙酮代谢的有用模型。
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