Department of Vascular Surgery, Henri Mondor Hospital, Créteil, France.
J Vasc Surg. 2010 Jun;51(6):1360-6. doi: 10.1016/j.jvs.2010.01.032. Epub 2010 Mar 29.
Aneurysmal involvement of the iliac bifurcation increases the level of difficulty during surgery for abdominal aortic aneurysm (AAA) repair, potentially increasing the risk of early postoperative complications. Three previous randomized trials comparing endovascular aneurysm repair (EVAR) and open repair (OR) for AAAs showed that EVAR is associated with a lower early mortality rate. However, whether these results are valid for AAA involving the iliac bifurcation (AAAIB) remains unclear. The aim of this study was to evaluate early and late results after OR and EVAR for patients with AAA involving the iliac bifurcation.
Of 1116 patients treated for elective AAA repair between January 1998 and January 2008, 131 presented with AAAIB as detected by computed tomography (CT) scan. Sixty-eight patients were treated by EVAR and 63 by OR. Clinical and anatomic data, operative intervention, and outcomes were collected prospectively and analyzed retrospectively. The median duration of follow-up was 38 months for both groups.
Patients in the EVAR group (72 +/- 10 years) were older than those in the OR group (64 +/- 8 years; P < .0001), but there were no differences in cardiac, renal, or pulmonary comorbidities between the two groups. Inhospital mortality rates were 2.9% vs 6.3% for EVAR and OR groups, respectively (P = .43). Systemic postoperative complications occurred in 7.4% vs 9.5% (P = .76) and postoperative colonic ischemia in 0% vs 6.3% (P = .051) of patients with EVAR and OR, respectively. Survival rates by Kaplan-Meier analysis were 91 +/- 7% for patients with EVAR and 90 +/- 8% for patients with OR at 2 years, and 61% +/- 15 for EVAR and 79% +/- 13 for OR at 5 years. All-cause reoperation rates were 25% with EVAR and 22% with OR (P = .83). Patients with EVAR were more likely to develop buttock claudication (33.3% vs 3.6%; P < .0001), whereas patients with OR were more prone to develop abdominal wall complications (19.6% vs 0%; P < .001).
In this series, the postoperative mortality and systemic complication rates after either EVAR or OR for AAAIB were not statistically different. In the OR group, there were more abdominal wall complications and a trend toward a higher rate of colonic ischemia. In the EVAR group, buttock claudication was more frequent.
在腹主动脉瘤(AAA)修复手术中,髂分叉处的动脉瘤累及会增加手术难度,可能会增加术后早期并发症的风险。三项比较血管内动脉瘤修复(EVAR)和开放修复(OR)治疗AAA 的随机试验表明,EVAR 与较低的早期死亡率相关。然而,这些结果是否适用于累及髂分叉的 AAA(AAAIB)尚不清楚。本研究旨在评估 OR 和 EVAR 治疗累及髂分叉的 AAA 患者的早期和晚期结果。
在 1998 年 1 月至 2008 年 1 月期间,对 1116 例接受择期 AAA 修复的患者进行了治疗,其中 131 例经计算机断层扫描(CT)扫描发现 AAAIB。68 例患者接受 EVAR 治疗,63 例患者接受 OR 治疗。前瞻性收集临床和解剖数据、手术干预和结果,并进行回顾性分析。两组的中位随访时间均为 38 个月。
EVAR 组(72 +/- 10 岁)患者年龄大于 OR 组(64 +/- 8 岁;P <.0001),但两组患者的心脏、肾脏或肺部合并症无差异。EVAR 组和 OR 组的院内死亡率分别为 2.9%和 6.3%(P =.43)。EVAR 组和 OR 组术后全身并发症发生率分别为 7.4%和 9.5%(P =.76),术后结肠缺血发生率分别为 0%和 6.3%(P =.051)。Kaplan-Meier 分析的生存率为 EVAR 组患者 2 年时为 91 +/- 7%,OR 组为 90 +/- 8%,5 年时 EVAR 组为 61% +/- 15%,OR 组为 79% +/- 13%。EVAR 组和 OR 组的全因再次手术率分别为 25%和 22%(P =.83)。EVAR 组患者更易出现臀部跛行(33.3%比 3.6%;P <.0001),而 OR 组患者更易发生腹壁并发症(19.6%比 0%;P <.001)。
在本系列中,EVAR 或 OR 治疗 AAAIB 后的术后死亡率和全身并发症发生率无统计学差异。在 OR 组中,腹壁并发症更多,结肠缺血的发生率有升高趋势。在 EVAR 组中,臀部跛行更为常见。