Microbiology and Parasitology Department, Universidad de Buenos Aires and the Hospital de Infecciosas Francisco Javier Muñiz, Juncal 3474, 4(a) piso C, Buenos Aires, CP 1425, Argentina.
Clin Dermatol. 2010 Mar 4;28(2):125-32. doi: 10.1016/j.clindermatol.2009.12.010.
Physicians have been aware of superficial fungal infections for centuries, but the causal agents and treatments of fungal infections remained unknown until the mid-1800s, when numerous important findings were reported. Among the relevant researchers in the field of superficial mycoses were Remak, who found the fungal nature of favus in 1837; Berg, who reported oral candidosis in 1841; and Wilkinson, who described vaginal candidosis in 1849. Tinea versicolor was described clinically in 1846 by Eichstedt, and its etiologic agent was identified in 1853. Beigel reported white piedra in 1856, and Cerqueira, tinea nigra in 1891. The book Les Tiegnes was published by Sabouraud in 1910, and black piedra infection was described by Horta in 1911. In 1927, Nannizzi reported the description of the sexual state of Microsporum gypseum. The current classification of dermatophytes was published by Emmons in 1934, and the taxonomy of yeast fungi was described by Lodder and Kreger-van Rij in 1952. Finally, the successful treatment of tinea capitis with griseofulvin by Gentles in 1958 saved many patients with tinea capitis from permanent hair loss, a common side effect after treatment with thallium. (c) 2010 Elsevier Inc. All rights reserved.
医生们几个世纪以来都了解浅表真菌感染，但直到 19 世纪中期，当许多重要的发现被报道后，才了解到真菌性感染的病原体和治疗方法。在浅部真菌病领域的相关研究人员中，Remak 在 1837 年发现了黄癣的真菌性质；Berg 在 1841 年报告了口腔念珠菌病；Wilkinson 在 1849 年描述了阴道念珠菌病。Tinea versicolor 在 1846 年由 Eichstedt 进行了临床描述，其病原体在 1853 年被鉴定出来。Beigel 在 1856 年报告了白癣，而 Cerqueira 在 1891 年报告了黑癣。Sabouraud 于 1910 年出版了《Les Tiegnes》一书，Horta 在 1911 年描述了黑结石感染。1927 年，Nannizzi 报告了石膏样小孢子菌有性状态的描述。1934 年，Emmons 发表了目前的皮肤癣菌分类，1952 年 Lodder 和 Kreger-van Rij 描述了酵母真菌的分类。最后，Gentles 在 1958 年用灰黄霉素成功治疗了头癣，使许多头癣患者免受永久性脱发的困扰，这是用铊治疗后的常见副作用。（c）2010 年爱思唯尔公司版权所有。
