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[蛆虫包括活体治疗慢性感染伤口的进展]

[Advancement of maggot including living body to treat chronic infected wounds].

作者信息

Zhang Zhen, Wang Shouyu, Diao Yunpeng, Zhang Houli, Huang Shanshan, Lv Decheng

机构信息

Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2009 Dec;34(24):3162-4.

Abstract

Human has used maggot to treat diseases for thousands of years. In recent years, with abuse of antibiotic and the rising incidence of antibiotic resistance, maggot therapy, as a surgical alternative, is mainly applied to treat chronic infected wounds on account of its low cost, efficacy and safety. Its mechanisms are disinfection, bio-debridement and enhancement of tissue regeneration. Maggot therapy which serves as a kind of biological therapy is promising. However, living maggot therapy could result in inevitable complications, so that we should apply traditional Chinese medicine theory to investigate and develop new delivery method of maggot. The review summarizes the past and present of maggot therapy.

摘要

人类使用蛆治疗疾病已有数千年历史。近年来,随着抗生素的滥用以及抗生素耐药性发病率的上升,蛆疗法作为一种外科替代方法,因其低成本、有效性和安全性,主要用于治疗慢性感染伤口。其机制包括消毒、生物清创和促进组织再生。蛆疗法作为一种生物疗法具有广阔前景。然而,活蛆疗法可能会导致不可避免的并发症,因此我们应运用中医理论来研究和开发蛆的新给药方法。本文综述了蛆疗法的过去和现状。

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