Qing Xue-mei, Liu Bao-yan, Wang Yong-yan
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100070.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2010 Jan;30(1):80-3.
Both "efficacy" and "effectiveness" are two important concepts in clinical evaluation. In this article, the differences and relationship between the two connotations were expounded, and both the differences between "explanatory randomized controlled trial (ERCT)" and "pragmatic randomized controlled trial (PRCT)", which are respectively corresponding to "efficacy" and "effectiveness", and their application values in different stages in clinical therapeutic effect evaluation were further explored. This study may be a helpful reference for defining research purposes, locating appropriate research stages, and choosing suitable designs at its different stages in the clinical evaluation process of Chinese medicine researches.
“疗效”和“效果”都是临床评价中的两个重要概念。本文阐述了二者内涵的差异与联系，并进一步探讨了分别与“疗效”和“效果”相对应的“解释性随机对照试验（ERCT）”和“实用性随机对照试验（PRCT）”之间的差异及其在临床疗效评价不同阶段的应用价值。本研究对于中医研究临床评价过程中明确研究目的、定位合适的研究阶段以及在不同阶段选择合适的设计可能具有一定的参考作用。
