Stenvinkel P, Hjelte L, Alván G, Hedman A, Hultman E, Strandvik B
Department of Nephrology, Karolinska Institute, Huddinge University Hospital, Sweden.
Acta Paediatr Scand. 1991 Feb;80(2):194-8. doi: 10.1111/j.1651-2227.1991.tb11833.x.
In 10 patients with cystic fibrosis (CF) and 10 controls of similar age quantitative segmental handling of sodium was estimated by lithium clearance. In the CF group, there was a tendency for an increased glomerular filtration rate (GFR) and increased absolute proximal sodium reabsorption. The fractional distal sodium reabsorption was significantly (p = 0.015) increased and sodium clearance was significantly (p less than 0.01) decreased in CF.
在10例囊性纤维化(CF)患者和10名年龄相仿的对照者中,通过锂清除率评估了钠的定量节段性处理情况。在CF组中,存在肾小球滤过率(GFR)升高和近端钠绝对重吸收增加的趋势。CF患者的远端钠重吸收分数显著升高(p = 0.015),钠清除率显著降低(p < 0.01)。