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囊性纤维化患者钠的肾脏清除率降低。

Decreased renal clearance of sodium in cystic fibrosis.

作者信息

Stenvinkel P, Hjelte L, Alván G, Hedman A, Hultman E, Strandvik B

机构信息

Department of Nephrology, Karolinska Institute, Huddinge University Hospital, Sweden.

出版信息

Acta Paediatr Scand. 1991 Feb;80(2):194-8. doi: 10.1111/j.1651-2227.1991.tb11833.x.

DOI:10.1111/j.1651-2227.1991.tb11833.x
PMID:2035310
Abstract

In 10 patients with cystic fibrosis (CF) and 10 controls of similar age quantitative segmental handling of sodium was estimated by lithium clearance. In the CF group, there was a tendency for an increased glomerular filtration rate (GFR) and increased absolute proximal sodium reabsorption. The fractional distal sodium reabsorption was significantly (p = 0.015) increased and sodium clearance was significantly (p less than 0.01) decreased in CF.

摘要

在10例囊性纤维化(CF)患者和10名年龄相仿的对照者中,通过锂清除率评估了钠的定量节段性处理情况。在CF组中,存在肾小球滤过率(GFR)升高和近端钠绝对重吸收增加的趋势。CF患者的远端钠重吸收分数显著升高(p = 0.015),钠清除率显著降低(p < 0.01)。

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