Department of Biology, Genetics Unit, Universidad Autonoma de Madrid, Madrid, spain.
Eur J Histochem. 2010 Jan 28;54(1):e2. doi: 10.4081/ejh.2010.e2.
The genome of stallion (Spanish breed) and donkey (Spanish endemic Zamorano-Leonés) were compared using whole comparative genomic in situ hybridization (W-CGH) technique, with special reference to the variability observed in the Y chromosome. Results show that these diverging genomes still share some highly repetitive DNA families localized in pericentromeric regions and, in the particular case of the Y chromosome, a sub-family of highly repeated DNA sequences, greatly expanded in the donkey genome, accounts for a large part of the chromatin in the stallion Y chromosome.
利用全比较基因组原位杂交（W-CGH）技术对西班牙马种种公马和西班牙特有扎莫拉诺-莱昂内斯驴的基因组进行了比较，特别关注了 Y 染色体上观察到的变异性。结果表明，这些分化的基因组仍有一些高度重复的 DNA 家族位于着丝粒区域，而在 Y 染色体的特殊情况下，一个高度重复的 DNA 序列亚家族在驴基因组中大量扩增，占据了种公马 Y 染色体中大部分染色质。
