放射治疗：脑转移瘤治疗中的神经认知考虑。
Radiotherapy: Neurocognitive considerations in the treatment of brain metastases.
机构信息
Department of Neurosurgery, The Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, ND-40, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
出版信息
Nat Rev Clin Oncol. 2010 Apr;7(4):185-6. doi: 10.1038/nrclinonc.2010.30.
The results of a randomized, controlled trial investigating the neurocognitive effects of stereotactic radiosurgery (SRS), with or without whole-brain radiation therapy (WBRT), to treat brain metastases demonstrated a significant reduction in learning and memory, associated with the addition of WBRT to SRS. the results indicate that SRS monotherapy is an effective and safe initial management strategy for brain metastases.
一项随机对照试验研究了立体定向放射外科（SRS）联合或不联合全脑放疗（WBRT）治疗脑转移瘤的神经认知效应，结果显示，与 SRS 联合 WBRT 相比，WBRT 的加入显著降低了学习和记忆能力。这些结果表明，SRS 单药治疗是脑转移瘤的一种有效且安全的初始治疗策略。
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