Department of Cancer Epidemiology and South Swedish Regional Tumour Registry, Lund University and Lund University Hospital, SE-221 85 Lund, Sweden.
Nat Rev Clin Oncol. 2010 Apr;7(4):191-3. doi: 10.1038/nrclinonc.2010.37.
Dose-dense administration of paclitaxel as well as intraperitoneal administration of platinum and paclitaxel as first-line treatments provide similar advantages compared with standard treatment in advanced ovarian cancer. Both approaches, however, need to be confirmed by additional studies. a low dose of pegylated liposomal doxorubicin combined with carboplatin is superior to standard paclitaxel and carboplatin in relapsed platinum-sensitive ovarian cancer.
与标准治疗相比,紫杉醇剂量密集疗法以及顺铂和紫杉醇腹腔内给药作为一线治疗在晚期卵巢癌中提供了相似的优势。然而,这两种方法都需要通过额外的研究来证实。在铂类敏感复发性卵巢癌中,低剂量聚乙二醇脂质体阿霉素联合卡铂优于标准紫杉醇和卡铂。