子宫脱垂和/或尿失禁手术后的症状性尿路感染。
Symptomatic urinary tract infections after surgery for prolapse and/or incontinence.
作者信息
Sutkin Gary, Alperin Marianna, Meyn Leslie, Wiesenfeld Harold C, Ellison Rennique, Zyczynski Halina M
机构信息
Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA, USA.
出版信息
Int Urogynecol J. 2010 Aug;21(8):955-61. doi: 10.1007/s00192-010-1137-x. Epub 2010 Mar 31.
INTRODUCTION AND HYPOTHESIS
The purpose of our study was to estimate the frequency and risk factors for symptomatic urinary tract infection (UTI) after surgery for stress urinary incontinence (SUI) and/or pelvic organ prolapse (POP).
METHODS
Case-control study of 389 consecutive women who underwent surgery for POP and/or SUI. Cases were defined as a symptomatic, culture-confirmed UTI within 6 weeks of surgery. Multivariable logistic regression was used to determine independent risk factors.
RESULTS
Thirty five (9%) women developed a UTI. The risk of UTI was significantly increased by previous history of multiple UTIs (adjusted OR: 3.7, CI 1.4-10.1), increased distance between the urethra and the anus (adjusted OR: 1.4, CI 1.1-1.9), and prolonged duration of catheterization (adjusted odds ratio (OR) for >or=10 days: 4.2, 95% CI 1.5-11.6); 94.6% of catheterizing women were prescribed daily nitrofurantoin.
CONCLUSIONS
UTI is an important postoperative morbidity after urogynecologic surgery and is common in catheterizing women despite antibiotic prophylaxis.
引言与假设
我们研究的目的是评估压力性尿失禁（SUI）和/或盆腔器官脱垂（POP）手术后有症状的尿路感染（UTI）的发生率及危险因素。
方法
对389例连续接受POP和/或SUI手术的女性进行病例对照研究。病例定义为术后6周内出现有症状的、经培养确诊的UTI。采用多变量逻辑回归确定独立危险因素。
结果
35例（9%）女性发生了UTI。既往有多次UTI病史（校正比值比：3.7，可信区间1.4 - 10.1）、尿道与肛门距离增加（校正比值比：1.4，可信区间1.1 - 1.9）以及导尿时间延长（导尿≥10天的校正比值比：4.2，95%可信区间1.5 - 11.6）会显著增加UTI风险；94.6%的导尿女性接受了每日呋喃妥因治疗。
结论
UTI是泌尿妇科手术后的一种重要术后并发症，尽管使用了抗生素预防，在导尿女性中仍很常见。
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