Department of General Surgery, Faculty of Medicine, Firat University, Elazig, Turkey.
Med Princ Pract. 2010;19(3):196-9. doi: 10.1159/000285286. Epub 2010 Mar 29.
To present a case of primary hepatic actinomycosis.
A-40-year-old man was admitted to the general surgery clinic with a 1-month history of abdominal pain and weight loss. Liver transaminase, bilirubin levels and white blood cell counts were increased. Abdominal ultrasound and CT revealed cystic lesions with necrotic debris involving the posterior segment of the right lobe of the liver and the medial segment of the left lobe.
The patient underwent surgery under general anesthesia. On exploration, three cavities were found within the liver containing necrotic material. Surgical debridement and drainage was performed. Histopathological examination revealed actinomycotic colonies with a surrounding suppurative granulomatous reaction. The patient was treated with penicillin for 3 months.
This case showed that histological examination of biopsy or surgical material or anaerobic cultures was needed for definitive diagnosis and that hepatic actinomycosis should be included in the differential diagnosis of solitary or multiple hypodense liver lesions.
介绍 1 例原发性肝放线菌病病例。
一名 40 岁男性因腹痛和体重减轻 1 个月就诊于普外科。肝转氨酶、胆红素和白细胞计数升高。腹部超声和 CT 显示右叶后段和左叶内侧段有含坏死碎屑的囊性病变。
患者全身麻醉下接受手术。探查时发现肝内有 3 个腔,其中含有坏死物质。行清创引流术。组织病理学检查显示放线菌菌落伴周围化脓性肉芽肿反应。患者接受青霉素治疗 3 个月。
本病例表明,明确诊断需要对活检或手术标本进行组织学检查或厌氧菌培养,肝放线菌病应纳入单发或多发肝低密度病变的鉴别诊断。