Yang Justin S, McElroy Mark J, Akbarnia Behrooz A, Salari Pooria, Oliveira Daniel, Thompson George H, Emans John B, Yazici Muharrem, Skaggs David L, Shah Suken A, Kostial Patricia N, Sponseller Paul D
Department of Orthopaedic Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
J Pediatr Orthop. 2010 Apr-May;30(3):264-70. doi: 10.1097/BPO.0b013e3181d40f94.
Growing rods are a commonly used form of growth guidance for patients with early onset scoliosis, but no studies exist to characterize their use among a large group of surgeons.
A survey regarding growing rod use preferences and a case-based survey regarding early onset scoliosis were completed by an international group of surgeons. Two hundred and sixty-five growing rod patients treated over 4.7+/-2.1 years in the Growing Spine Study Group database were analyzed to characterize actual practice and compare it with the survey results. All patients had at least 2 years of treatment.
In the case-based survey, there was correlation (P=0.04, r=0.58) between increasing curve size and choice of growing rods over nonoperative treatment, rib-based distraction (vertically expandable prosthetic titanium rib), growth guidance (Shilla), and primary fusion. In practice, growing rods were used for most types of early onset spine deformity. Most surgeons stated that their indication for growing rod treatment was a curve over 60 degrees (10/13) in a patient younger than 8 to 10 years (14/17). In practice, mean curve at rod insertion was 73+/-20 degrees and age was 6.0+/-2.5 years. Other factors favoring growing rods included curve rigidity (8/17), brace intolerance (6/17) and syndromic diagnoses (2/17). In the database, idiopathic scoliosis represented <50% of diagnoses. The most common preferred surgical lengthening interval was 6 months. However, in practice, lengthening actually occurred at a mean of 8.6+/-5.1 months. In the database, the number of growing rod insertions per year (P=0.02, r=0.96) and percentage of surgeons using dual rods over single rods (P=0.065, r=0.93) increased over time. Insertion age (P=0.075, r=-0.87) and lengthening interval (P=0.006, r=-0.69) decreased as time progressed. The most common stated indication on the survey for final fusion was skeletal maturity (13/17), and 7/13 surgeons used Risser 3 or more. Indications to stop lengthening included complications such as infection or implant failure (14/17), curves progressing past 90 degrees (8/17), and failure to distract (6/13). The most common method of final fusion was replacement of implants with more intermediate anchors.
Significant practice variation exists in growing rod treatment, but there is some consensus on indications for surgery including curve size, diagnosis and age, and lengthening intervals and final fusion methods. Mean curve size and lengthening interval are greater in practice than in surgeons' stated aims. In principle and in practice, most growing rods are used for curves over 60 degrees in patients under 10, in all diagnoses. This information may form a starting point as practice variation is studied.
生长棒是早发性脊柱侧弯患者常用的生长引导方式,但尚无研究对大量外科医生使用生长棒的情况进行描述。
一个国际外科医生团队完成了一项关于生长棒使用偏好的调查以及一项基于病例的早发性脊柱侧弯调查。对生长脊柱研究组数据库中在4.7±2.1年期间接受治疗的265例生长棒治疗患者进行分析,以描述实际治疗情况并与调查结果进行比较。所有患者至少接受了2年治疗。
在基于病例的调查中,随着侧弯度数增加,选择生长棒而非非手术治疗、肋骨撑开(垂直可扩展人工钛肋骨)、生长引导(Shilla)和初次融合之间存在相关性(P = 0.04,r = 0.58)。在实际应用中,生长棒用于大多数类型的早发性脊柱畸形。大多数外科医生表示,他们进行生长棒治疗的指征是8至10岁以下患者侧弯超过60度(10/13)。在实际治疗中,置入生长棒时的平均侧弯度数为73±20度,年龄为6.0±2.5岁。其他倾向于使用生长棒的因素包括侧弯僵硬(8/17)、支具不耐受(6/17)和综合征性诊断(2/17)。在数据库中,特发性脊柱侧弯的诊断比例不到50%。最常用的手术延长间隔时间是6个月。然而,在实际治疗中,延长的平均时间为8.6±5.1个月。在数据库中,每年生长棒置入的数量(P = 0.02,r = 0.96)以及使用双棒而非单棒的外科医生比例(P = 0.065,r = 0.93)随时间增加。随着时间推移,置入年龄(P = 0.075,r = -0.87)和延长间隔时间(P = 0.006,r = -0.69)减少。调查中最常提及的最终融合指征是骨骼成熟(13/17),7/13的外科医生使用Risser 3级或更高等级。停止延长的指征包括感染或植入物失败等并发症(14/17)、侧弯进展超过90度(8/17)以及撑开失败(6/13)。最常用的最终融合方法是用更多中间锚钉替换植入物。
生长棒治疗存在显著的实际差异,但在手术指征方面存在一些共识,包括侧弯度数、诊断和年龄、延长间隔时间以及最终融合方法。实际治疗中的平均侧弯度数和延长间隔时间大于外科医生所述的目标。原则上和实际应用中,大多数生长棒用于所有诊断类型中10岁以下侧弯超过60度的患者。随着对实际差异的研究,这些信息可作为一个起点。