Department of Medicine, University of Alberta, 8440-112th Street, Edmonton, Alberta, T6G 2B7, Canada.
Osteoporos Int. 2011 Jan;22(1):223-30. doi: 10.1007/s00198-010-1212-7. Epub 2010 Apr 1.
Few outpatients with fractures are treated for osteoporosis in the years following fracture. In a randomized pilot study, we found a nurse case-manager could double rates of osteoporosis testing and treatment compared with a proven efficacious quality improvement strategy directed at patients and physicians (57% vs 28% rates of appropriate care).
Few patients with fractures are treated for osteoporosis. An intervention directed at wrist fracture patients (education) and physicians (guidelines, reminders) tripled osteoporosis treatment rates compared to controls (22% vs 7% within 6 months of fracture). More effective strategies are needed.
We undertook a pilot study that compared a nurse case-manager to the multifaceted intervention using a randomized trial design. The case-manager counseled patients, arranged bone mineral density (BMD) tests, and prescribed treatments. We included controls from our first trial who remained untreated for osteoporosis 1-year post-fracture. Primary outcome was bisphosphonate treatment and secondary outcomes were BMD testing, appropriate care (BMD test-treatment if bone mass low), and costs.
Forty six patients untreated 1-year after wrist fracture were randomized to case-manager (n = 21) or multifaceted intervention (n = 25). Median age was 60 years and 68% were female. Six months post-randomization, 9 (43%) case-managed patients were treated with bisphosphonates compared with 3 (12%) multifaceted intervention patients (relative risk [RR] 3.6, 95% confidence intervals [CI] 1.1-11.5, p = 0.019). Case-managed patients were more likely than multifaceted intervention patients to undergo BMD tests (81% vs 52%, RR 1.6, 95%CI 1.1-2.4, p = 0.042) and receive appropriate care (57% vs 28%, RR 2.0, 95%CI 1.0-4.2, p = 0.048). Case-management cost was $44 (CDN) per patient vs $12 for the multifaceted intervention.
A nurse case-manager substantially increased rates of appropriate testing and treatment for osteoporosis in patients at high-risk of future fracture when compared with a multifaceted quality improvement intervention aimed at patients and physicians. Even with case-management, nearly half of patients did not receive appropriate care.
clinicaltrials.gov identifier: NCT00152321.
很少有骨折门诊患者在骨折后数年接受骨质疏松症治疗。在一项随机试点研究中,我们发现护士病例管理者可以将骨质疏松症检测和治疗率提高一倍,而不是将其作为针对患者和医生的经过验证的有效质量改进策略(适当护理的比例为 57%,而不是 28%)。
很少有骨折患者接受骨质疏松症治疗。一项针对腕部骨折患者(教育)和医生(指南、提醒)的干预措施使骨质疏松症治疗率增加了两倍,与对照组相比(骨折后 6 个月内,22%对 7%)。需要更有效的策略。
我们进行了一项试点研究,比较了护士病例管理者与多方面干预措施,采用随机试验设计。病例管理者对患者进行咨询,安排骨密度(BMD)检查,并开出治疗方案。我们纳入了来自我们首次试验的对照组,这些患者在骨折后 1 年仍未接受骨质疏松症治疗。主要结果是双膦酸盐治疗,次要结果是 BMD 检测、适当护理(如果骨量低则进行 BMD 检测-治疗)和成本。
46 名手腕骨折后 1 年未接受治疗的患者被随机分配到病例管理者(n=21)或多方面干预组(n=25)。中位年龄为 60 岁,68%为女性。随机分组后 6 个月,9 名(43%)病例管理者治疗患者接受双膦酸盐治疗,而 5 名(12%)多方面干预治疗患者接受双膦酸盐治疗(相对风险 [RR] 3.6,95%置信区间 [CI] 1.1-11.5,p=0.019)。病例管理者治疗患者比多方面干预治疗患者更有可能接受 BMD 检查(81%比 52%,RR 1.6,95%CI 1.1-2.4,p=0.042),并接受适当护理(57%比 28%,RR 2.0,95%CI 1.0-4.2,p=0.048)。病例管理的成本为每个患者 44 加元(加拿大元),而多方面干预的成本为 12 加元。
与针对患者和医生的多方面质量改进干预措施相比,护士病例管理者大大提高了高危骨折患者骨质疏松症的适当检测和治疗率。即使有病例管理,近一半的患者仍未接受适当的护理。
clinicaltrials.gov 标识符:NCT00152321。