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[1型糖尿病儿童及青少年肾脏的超声特征]

[The ultrasound characteristics of kidneys in children and adolescents with diabetes mellitus type 1].

作者信息

Hasanović Evlijana, Tulumović Denijal, Imamović Goran, Trnacević Senaid

机构信息

Klinika za djecije bolesti, Univerzitetski klinicki centar Tuzla, 75 000 Tuzla, Bosna i Hercegovina.

出版信息

Lijec Vjesn. 2010 Jan-Feb;132(1-2):13-7.

Abstract

The aim of the study was to compare ultrasound findings of morphometric measurements and registration of Doppler signs of kidneys between children and adolescents with diabetes mellitus type 1 (DMT1) with microalbuminuria, and metabolic control with duration of the disease. Retrospective-prospective study included 80 patients, who got DMT1 in the age from 2 to 16 years. In relation to the duration of the disease, all patients were divided into two groups: the first was whose illness had lasted less than 10 years, the second group was with duration of DMT1 more than 10 years. In patients with duration of DMT1 more than 10 years, the frequency of microalbuminuria, pathological findings of the volume of right kidney, and higher HbA1C were significantly greater. The significant difference was found in the frequency of pathological findings of the resistance index (RI) in the interlobar arteries in both kidneys. Alongside microalbuminuria, monitoring the dimension and volume of the kidneys may indicate the existence of the early phases of diabetic nephropathy.

摘要

该研究的目的是比较1型糖尿病(DMT1)合并微量白蛋白尿的儿童和青少年肾脏形态测量的超声检查结果、肾脏多普勒征象的记录情况,以及代谢控制与病程之间的关系。回顾性-前瞻性研究纳入了80例2至16岁患DMT1的患者。根据病程长短,所有患者被分为两组:第一组疾病持续时间少于10年,第二组DMT1病程超过10年。在DMT1病程超过10年的患者中,微量白蛋白尿的发生率、右肾体积的病理表现以及更高的糖化血红蛋白(HbA1C)水平均显著更高。在双侧肾脏叶间动脉阻力指数(RI)的病理表现发生率上发现了显著差异。除微量白蛋白尿外,监测肾脏的尺寸和体积可能提示糖尿病肾病早期阶段的存在。

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