Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Eur J Cardiothorac Surg. 2010 Sep;38(3):299-304. doi: 10.1016/j.ejcts.2010.02.013. Epub 2010 Mar 31.
The treatment of thoraco-abdominal aortic aneurysms (TAAAs) is extremely laborious, due to the surgical complexity of this condition. In particular, postoperative spinal paraplegia poses a severe complication that significantly lowers patient's quality of life. In 1997, we devised a hybrid procedure consisting of extended endovascular aortic repair (EVAR) and visceral reconstruction. In this article, we report the long-term results obtained from this procedure.
We conducted 1106 endovascular aortic repairs between 1997 and 2008. Among these, we selected 86 cases of TAAA. The mean patient age was 71.6 years. Preoperative complications included 19 cases of stroke, 22 cases of coronary artery disease (CAD) and 16 cases of chronic obstructive pulmonary disease (COPD). Cerebrospinal fluid drainage was initiated during the operation. We performed bypasses from the aortic bifurcation to abdominal visceral arteries, and deployed stent grafts to exclude the entire TAAA.
Operative time averaged 386 min. We lost two patients and encountered only one case of graft occlusion. Two patients had acute renal failure, but neither required a tracheostomy. Furthermore, no patients exhibited paraplegia or delayed paraplegia. We observed endoleaks in nine cases, and shrunken aneurysms in 73 cases. Long-term results included survival rates of 94.8%, 85.8%, 80.2% and 66.6% at 2, 5, 8 and 10 years, respectively. Only two patients died from aortic events. Rates of freedom from aortic events were 90.7%, 80.6%, 70.8% and 70.8% at 2, 5, 8 and 10 years, respectively.
The hybrid TAAA-repair protocol yielded satisfactory results. Although thorough follow-up is required for visceral bypass, this procedure could become the standard for TAAAs.
胸主动脉腹主动脉瘤(TAAA)的治疗非常费力,因为这种情况的手术复杂性很高。特别是,术后脊髓瘫痪是一种严重的并发症,大大降低了患者的生活质量。1997 年,我们设计了一种混合手术,包括延长的血管内主动脉修复(EVAR)和内脏重建。在本文中,我们报告了该手术的长期结果。
我们在 1997 年至 2008 年间进行了 1106 例血管内主动脉修复。在这些患者中,我们选择了 86 例 TAAA 患者。患者平均年龄为 71.6 岁。术前并发症包括 19 例中风,22 例冠心病(CAD)和 16 例慢性阻塞性肺疾病(COPD)。术中开始进行脑脊液引流。我们在主动脉分叉处到腹部内脏动脉之间进行旁路手术,并放置支架移植物以排除整个 TAAA。
手术时间平均为 386 分钟。我们失去了两名患者,仅发生了一例移植物闭塞。两名患者出现急性肾功能衰竭,但均无需行气管切开术。此外,没有患者出现截瘫或迟发性截瘫。我们观察到 9 例内漏,73 例动脉瘤缩小。长期结果包括 2、5、8 和 10 年的生存率分别为 94.8%、85.8%、80.2%和 66.6%。仅有两名患者因主动脉事件死亡。2、5、8 和 10 年的主动脉事件无事件生存率分别为 90.7%、80.6%、70.8%和 70.8%。
杂交 TAAA 修复方案取得了满意的结果。尽管需要对内脏旁路进行彻底随访,但该手术可能成为 TAAA 的标准治疗方法。