College of Pharmacy, University of Illinois at Chicago, 833 S. Wood Street, Chicago, IL 60612, USA.
Am J Health Syst Pharm. 2010 Apr 15;67(8 Suppl 4):S9-12. doi: 10.2146/ajhp100093.
To describe the components of and factors contributing to the costs of inhaled anesthesia, basis for quantifying and comparing these costs, and practical strategies for performing pharmacoeconomic analyses and reducing the costs of inhaled anesthetic agents.
Inhaled anesthesia can be costly, and some of the variable costs, including fresh gas flow rates and vaporizer settings, are potential targets for cost savings. The use of a low fresh gas flow rate maximizes rebreathing of exhaled anesthetic gas and is less costly than a high flow rate, but it provides less control of the level of anesthesia. The minimum alveolar concentration (MAC) hour is a measure that can be used to compare the cost of inhaled anesthetic agents at various fresh gas flow rates. Anesthesia records provide a sense of patterns of inhaled anesthetic agent use, but the amount of detail can be limited. Cost savings have resulted from efforts to reduce the direct costs of inhaled anesthetic agents, but reductions in indirect costs through shortened times to patient recovery and discharge following the judicious use of these agents are more difficult to demonstrate. The patient case mix, fresh gas flow rates typically used during inhaled anesthesia, availability and location of vaporizers, and anesthesia care provider preferences and practices should be taken into consideration in pharmacoeconomic evaluations and recommendations for controlling the costs of inhaled anesthesia.
Understanding factors that contribute to the costs of inhaled anesthesia and considering those factors in pharmacoeconomic analyses and recommendations for use of these agents can result in cost savings.
描述吸入麻醉的成本构成和影响因素,为量化和比较这些成本提供依据,并介绍实施药物经济学分析和降低吸入麻醉剂成本的实用策略。
吸入麻醉的费用较高,一些可变动成本,包括新鲜气体流量和蒸发器设置,是节省成本的潜在目标。使用低新鲜气体流量可最大限度地重复吸入呼出的麻醉气体,成本低于高流量,但对麻醉水平的控制较差。肺泡最低有效浓度(MAC)小时是一种可以用来比较不同新鲜气体流量下吸入麻醉剂成本的衡量标准。麻醉记录可以了解吸入麻醉剂使用的模式,但详细程度可能有限。通过努力降低吸入麻醉剂的直接成本已经实现了成本节约,但通过明智地使用这些药物来缩短患者恢复和出院时间,从而降低间接成本则更难证明。在药物经济学评估和控制吸入麻醉成本的建议中,应考虑患者病例组合、吸入麻醉期间通常使用的新鲜气体流量、蒸发器的可用性和位置,以及麻醉护理提供者的偏好和实践。
了解影响吸入麻醉成本的因素,并在药物经济学分析和使用这些药物的建议中考虑这些因素,可以节省成本。