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减肥手术:2型糖尿病的前沿治疗方法?

Bariatric surgery: a cutting-edge cure for Type 2 diabetes?

作者信息

Coleman James, Phillips Simon

机构信息

Department of Medical Education, Maurice Shock Medical Sciences Building, University of Leicester, PO Box 138, Leicester, LE1 9HN, UK. email:

出版信息

N Z Med J. 2010 Mar 19;123(1311):65-8.

Abstract

Type 2 diabetes is rapidly becoming a global health crisis. It is associated with multiple comorbidities and is placing an ever increasing financial burden on society. There is now a need to explore new methods of tackling this problem. A growing pool of evidence suggests that bariatric surgery has the potential to cure Type 2 diabetes in a select population and provide additional benefits for many of its associated comorbidities. Whilst there are various proposals that explain these phenomena, current research suggests the cause is mainly due to increased post surgical release of insulin promoting gut hormones. The aim of this paper is to introduce some of the complex issues surrounding the use of bariatric surgery in Type 2 diabetes and highlight the controversial aspects encompassing this topic.

摘要

2型糖尿病正迅速成为一场全球健康危机。它与多种合并症相关联,给社会带来日益沉重的经济负担。现在有必要探索解决这一问题的新方法。越来越多的证据表明,减肥手术有可能治愈特定人群的2型糖尿病,并为其许多相关合并症带来额外益处。虽然有各种解释这些现象的提议,但目前的研究表明,其原因主要是术后促进胰岛素分泌的肠道激素释放增加。本文的目的是介绍一些围绕减肥手术在2型糖尿病治疗中应用的复杂问题,并突出该主题中存在争议的方面。

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