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减重手术作为 2 型糖尿病“治愈”方法对外科领域的影响。

The implications for the surgical community of bariatric surgery as a "cure" for type 2 diabetes.

出版信息

Am J Surg. 2013 Jul;206(1):136-41. doi: 10.1016/j.amjsurg.2012.11.013.

DOI:10.1016/j.amjsurg.2012.11.013
PMID:23790217
Abstract

The United States is in the throes of an epidemic of morbid obesity and, parenthetically, type 2 diabetes. Recent data indicate that bariatric surgery, notably Roux-en-Y gastric bypass, is valid not only for weight loss but also for a high success rate in the amelioration and perhaps "cure" of type 2 diabetes. It clearly is not weight loss alone, because the amelioration of type 2 diabetes occurs before weight loss. The mechanism needs to be elucidated and researched. For the first time since tuberculosis--before antitubercular drugs, when surgical procedures were the principal mechanism for dealing with tuberculosis--surgery has the opportunity to participate in the amelioration and perhaps cure of this epidemic and to regain its professional stature. Included in this article are the author's thoughts and suggestions on how we can keep control of weight loss and bariatric procedures that are valid treatments for morbid obesity and related type 2 diabetes. We should use this opportunity to stop the current conversion of surgeons from professionals to employees.

摘要

美国正处于病态肥胖症的流行之中,顺便说一句,还有 2 型糖尿病。最近的数据表明,减重手术,特别是 Roux-en-Y 胃旁路手术,不仅对减肥有效,而且对 2 型糖尿病的改善甚至“治愈”也有很高的成功率。这显然不仅仅是减肥,因为 2 型糖尿病的改善发生在体重减轻之前。需要阐明和研究其机制。这是自结核病以来的第一次——在抗结核药物之前,当时手术是治疗结核病的主要手段——手术有机会参与改善甚至治愈这种流行疾病,并重新获得其专业地位。本文还包括作者关于如何控制体重减轻和减重手术的想法和建议,这些手术是治疗病态肥胖症和相关 2 型糖尿病的有效方法。我们应该利用这个机会阻止目前将外科医生从专业人员转变为员工的趋势。

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引用本文的文献

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Sleeve Gastrectomy and Type 2 Diabetes Mellitus: a Systematic Review of Long-Term Outcomes.袖状胃切除术与2型糖尿病:长期疗效的系统评价
Obes Surg. 2016 Jul;26(7):1616-21. doi: 10.1007/s11695-016-2188-y.
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Downgrading of type 2 diabetes mellitus (T2DM) after obesity surgery: duration and severity matter.肥胖手术后2型糖尿病(T2DM)的病情缓解:病程和严重程度很重要。
Obes Surg. 2015 Mar;25(3):494-9. doi: 10.1007/s11695-014-1419-3.