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关节内注射布比卡因后经关节内疼痛泵导管导致盂肱关节软骨溶解症:18 例报告。

Chondrolysis of the glenohumeral joint after infusion of bupivacaine through an intra-articular pain pump catheter: a report of 18 cases.

机构信息

Division of Orthopaedic Surgery, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

出版信息

Arthroscopy. 2010 Apr;26(4):451-61. doi: 10.1016/j.arthro.2010.01.022.

Abstract

PURPOSE

To report on our experience of patients who received infusion of bupivacaine with epinephrine after arthroscopic glenoid labral repair surgery and in whom glenohumeral joint chondrolysis subsequently developed, as well as to determine the incidence of such chondrolysis in our surgeons' patient populations.

METHODS

A retrospective chart review of 18 patients diagnosed with chondrolysis was carried out. All patients were from 2 experienced orthopaedic surgeons' practices. Details of their clinical course were obtained and summarized. These data were compared with all other arthroscopies completed by the 2 surgeons to determine the incidence of chondrolysis.

RESULTS

All 18 patients diagnosed with glenohumeral joint chondrolysis received postoperative infusion of bupivacaine with epinephrine through an intra-articular pain pump catheter (IAPPC). None of the patients received thermal energy as part of their procedure. None of the patients had evidence of glenohumeral joint infection, although an extensive workup was frequently undertaken. Clinically, patients presented with a stiff, painful shoulder. Examination showed decreased range of motion of the affected shoulder. Radiographs and magnetic resonance imaging showed joint space narrowing, as well as subchondral sclerosis and cyst formation. Of the 18 patients, 14 have since undergone repeat arthroscopic procedures, and 5 have received a humeral head-resurfacing operation. Within the same time period, there were 113 arthroscopies, with 45 pain pumps used. Chondrolysis developed in 16 of 32 patients with high-flow IAPPCs and 2 of 12 patients with low-flow IAPPCs (1 patient's IAPPC flow rate was not documented).

CONCLUSIONS

Although we cannot establish a causal link, the development of glenohumeral chondrolysis may be related to the intra-articular infusion of bupivacaine with epinephrine postoperatively. We thus caution against the use of IAPPCs.

LEVEL OF EVIDENCE

Level IV, therapeutic case series.

摘要

目的

报告我们在关节镜下盂唇修补术后接受布比卡因肾上腺素输注的患者中出现肱盂关节软骨溶解的经验,并确定这种软骨溶解在我们外科医生的患者群体中的发生率。

方法

对 18 例诊断为软骨溶解的患者进行回顾性图表审查。所有患者均来自 2 位经验丰富的骨科医生的实践。获得并总结了他们的临床过程的详细信息。将这些数据与 2 位外科医生完成的所有其他关节镜检查进行比较,以确定软骨溶解的发生率。

结果

所有 18 例诊断为肱盂关节软骨溶解的患者均通过关节内疼痛泵导管(IAPPC)接受术后布比卡因肾上腺素输注。没有患者接受热能作为其手术的一部分。尽管经常进行广泛的检查,但所有患者均无肱盂关节感染的证据。临床上,患者表现为僵硬、疼痛的肩部。检查显示受影响的肩部活动范围减小。射线照相和磁共振成像显示关节间隙变窄,以及软骨下硬化和囊肿形成。在这 18 例患者中,有 14 例随后接受了重复关节镜手术,有 5 例接受了肱骨头表面置换手术。在同一时期,有 113 例关节镜检查,其中使用了 45 个疼痛泵。高流量 IAPPC 中有 16 例和低流量 IAPPC 中有 2 例(1 例患者的 IAPPC 流速未记录)出现软骨溶解。

结论

尽管我们无法建立因果关系,但肱盂关节软骨溶解的发展可能与术后关节内布比卡因肾上腺素输注有关。因此,我们警告不要使用 IAPPC。

证据水平

IV 级,治疗性病例系列。

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