University of Washington, Seattle, Washington, USA.
J Bone Joint Surg Am. 2011 Apr 6;93(7):615-25. doi: 10.2106/JBJS.I.01386. Epub 2011 Feb 25.
Glenohumeral chondrolysis is a complication of arthroscopic shoulder surgery characterized by the dissolution of the articular cartilage of the glenoid and the humeral head. An analysis of 375 intra-articular shoulder arthroscopic surgical procedures by an individual community orthopaedic surgeon was performed to explore which factors or combinations of factors might be associated with glenohumeral chondrolysis.
The occurrence of chondrolysis was correlated with several demographic and surgical variables with use of hazard ratios from Cox proportional hazards models and Kaplan-Meier survivorship curves. Sensitivity analysis was used to examine the effect of two different definitions of the date of the onset of chondrolysis.
In this cohort, each case of documented chondrolysis was associated with the intra-articular post-arthroscopic infusion of a local anesthetic, either Marcaine (bupivacaine) or lidocaine. In an analysis of the group that received an intra-articular postoperative infusion of a local anesthetic, the risk of chondrolysis was found to be greater for those with one or more suture anchors placed in the glenoid, for younger patients, and for those who had the surgery near the end of the ten-year study period.
To our knowledge, this is the first Level-II retrospective cohort study of the factors associated with the development of post-arthroscopic glenohumeral chondrolysis. In this cohort of intra-articular shoulder arthroscopic procedures, chondrolysis was observed only in cases in which either Marcaine or lidocaine had been infused into the joint during the postoperative period. Avoiding such a postoperative infusion may reduce the risk of chondrolysis.
关节镜肩关节手术后的肱盂软骨溶解症是一种并发症,其特征为关节盂和肱骨头的关节软骨溶解。对一位社区骨科医生进行的 375 例关节内肩关节关节镜手术进行了分析,以探讨哪些因素或因素组合可能与肱盂软骨溶解症有关。
使用 Cox 比例风险模型的风险比和 Kaplan-Meier 生存曲线,将软骨溶解的发生与几个人口统计学和手术变量相关联。敏感性分析用于检查两种不同的软骨溶解发病日期定义的影响。
在本队列中,每例有记录的软骨溶解病例都与关节镜术后关节内局部麻醉剂(布比卡因或利多卡因)的输注有关。在对接受关节内术后局部麻醉剂输注的组进行分析时,发现以下情况的软骨溶解风险更高:在关节盂中放置一个或多个缝线锚钉、患者更年轻、以及手术接近十年研究期的尾声时进行手术。
据我们所知,这是第一份关于与关节镜下肱盂软骨溶解症发展相关因素的 II 级回顾性队列研究。在本关节内肩关节关节镜手术队列中,仅在术后关节内输注甲哌卡因或利多卡因的情况下观察到软骨溶解。避免这种术后输注可能会降低软骨溶解的风险。