Walton R C, Ball S F, Joffrion V C
Department of Ophthalmology, Ochsner Clinic, New Orleans, Louisiana.
Br J Ophthalmol. 1991 May;75(5):270-2. doi: 10.1136/bjo.75.5.270.
Glaucoma is considered to be an uncommon complication of Hansen's disease (leprosy). This study determined the prevalence and characteristics of glaucoma in a large institutionalised leprosy population. All 193 patients currently residing at the Gillis W Long Hansen's Disease Center received a complete ophthalmic examination and review of their records. All had been previously treated with dapsone and/or clofazimine. Based on the strict definition of a recorded intraocular pressure greater than or equal to 22 mm Hg and characteristic optic nerve pathology, 19 patients (10%) were found to have glaucoma. Glaucoma secondary to uveitis was noted in 11 of these patients. These findings suggest that the chronic inflammatory process of Hansen's disease, even when treated, may be followed by secondary glaucoma. We recommend that all patients with Hansen's disease receive regular periodic examinations, including slit-lamp biomicroscopy to detect low-grade iridocyclitis and measurement of intraocular pressure.
青光眼被认为是汉森病（麻风病）的一种罕见并发症。本研究确定了大型麻风病住院人群中青光眼的患病率及特征。所有目前居住在吉利斯·W·朗汉森病中心的193名患者均接受了全面的眼科检查并查阅了他们的病历。所有患者此前均接受过氨苯砜和/或氯法齐明治疗。根据记录的眼压大于或等于22毫米汞柱以及特征性视神经病变的严格定义，发现19名患者（10%）患有青光眼。其中11名患者存在葡萄膜炎继发的青光眼。这些发现表明，即使经过治疗，汉森病的慢性炎症过程仍可能继发青光眼。我们建议所有汉森病患者接受定期检查，包括裂隙灯生物显微镜检查以检测轻度虹膜睫状体炎和测量眼压。
