Fang Hsiu-Yu, Chung Sheng-Ying, Sun Cheuk-Kwan, Youssef Ali A, Bhasin Anuj, Tsai Tzu-Hsien, Yang Cheng-Hsu, Chen Chien-Jen, Hussein Hisham, Wu Chiung-Jen, Yip Hon-Kan
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Ann Vasc Surg. 2010 Jul;24(5):670-9. doi: 10.1016/j.avsg.2009.12.001. Epub 2010 Apr 3.
The purpose of this study was to introduce a novel and safe technique with high procedural success for carotid artery stenting (CAS).
From April 2004 to May 2009, 161 patients underwent CAS using either a high transradial arterial approach (TRA, defined as 10 cm above styloid process) or a transbrachial arterial approach (TBA) with a 7F arterial sheath. Selective carotid angiography was performed using a 6F Kimny guiding catheter and Teflon wire (260 cm in length) by Catheter Looping And Retrograde Engagement Technique (CLARET) with the guiding catheter seated on the right coronary cusp and its tip engaged into the common carotid artery (CCA). Teflon wire was introduced into the CCA again after the diagnostic procedure, followed by replacement of the 6F Kimny guiding catheter by a 7F Kimny catheter for CAS using one of the following techniques: (1) direct-engagement method, i.e., from right innominate artery into the right CCA; (2) looping method plus double-wire technique (utilized two Teflon wires to provide an adequate support) for both the right and left CCA; and (3) looping method plus a PercuSurge balloon anchoring at the external carotid artery.
This distinctive technique offered 100% diagnostic success and 99.4% CAS success. Two patients (1.2%) experienced major ischemic stroke after CAS and two (1.2%) died during hospitalization.
The results of the present study showed that high TRA/TBA using CLARET for CAS in patients with severe carotid artery stenosis is safe and technically feasible with an extremely high success rate.
本研究的目的是介绍一种用于颈动脉支架置入术(CAS)的新颖且安全、手术成功率高的技术。
2004年4月至2009年5月,161例患者采用经桡动脉高位入路(TRA,定义为在茎突上方10 cm处)或经肱动脉入路(TBA)并使用7F动脉鞘进行CAS。使用6F Kimny引导导管和特氟龙导丝(长度为260 cm),通过导管环行和逆行嵌入技术(CLARET)进行选择性颈动脉血管造影,引导导管置于右冠状动脉瓣上,其尖端嵌入颈总动脉(CCA)。诊断性操作后,再次将特氟龙导丝引入CCA,然后用7F Kimny导管替换6F Kimny引导导管,采用以下技术之一进行CAS:(1)直接嵌入法,即从右无名动脉进入右CCA;(2)环行法加双导丝技术(使用两根特氟龙导丝提供足够支撑)用于左右CCA;(3)环行法加在颈外动脉处使用PercuSurge球囊锚定。
这种独特的技术诊断成功率为100%,CAS成功率为99.4%。两名患者(1.2%)在CAS后发生严重缺血性卒中,两名患者(1.2%)在住院期间死亡。
本研究结果表明,对于严重颈动脉狭窄患者,使用CLARET进行高位TRA/TBA的CAS是安全的,技术上可行,成功率极高。