Department of Health and Kinesiology, Georgia Southern University, Statesboro, Georgia, USA.
Nutrition. 2010 Nov-Dec;26(11-12):1031-7. doi: 10.1016/j.nut.2009.12.003. Epub 2010 Apr 3.
It has been estimated that approximately 220,000 people with morbid obesity underwent bariatric surgery in 2008. Modification of the gastrointestinal tract affects absorption and health care professionals counseling bariatric patients need to be aware of possible micronutrient deficiencies and their symptoms. A systematic review of several databases and bariatric surgery center websites on the Internet was conducted from January 1980 to July 2009 to identify literature related to micronutrient deficiencies occurring after bariatric surgery. Keywords used individually or in combination were bariatric surgery, obesity, vitamin/mineral deficiencies, altered gastrointestinal function, nutrient absorption, nutrient supplementation, and metabolic complications, and were variously combined in the search list. Based on this review, all patients scheduled for bariatric surgery should receive daily multivitamin and multitrace mineral supplements. The literature suggests that bariatric surgery patients are at risk for deficiency of the following nutrients after surgery: vitamins B(12), B(1), C, folate, A, D, and K, along with the trace minerals iron, selenium, zinc, and copper. Over-the-counter multivitamin and mineral supplements do not provide adequate amounts of certain nutrients such as vitamin B(12), iron, or fat-soluble vitamins and patients will require additional doses of prophylactic supplementation life-long to maintain optimal micronutrient status. In addition, preconception care for adequate prenatal supplementation is critical for pregnant women who have undergone bariatric surgery, as iron, vitamin A, vitamin B(12), vitamin K, and folate deficiencies are associated with maternal and fetal complications, including severe anemia, congenital abnormalities, low birth weight, and failure to thrive. All bariatric surgery patients would be best served by receiving regular monitoring of serum nutrient levels starting at 3 mo after surgery and periodically thereafter.
据估计,2008 年约有 22 万人患有病态肥胖症,并接受了减肥手术。胃肠道的改变会影响吸收,为肥胖症患者提供咨询服务的医疗保健专业人员需要了解可能出现的微量营养素缺乏及其症状。从 1980 年 1 月至 2009 年 7 月,对几个数据库和互联网上的减肥手术中心网站进行了系统回顾,以确定与减肥手术后发生的微量营养素缺乏相关的文献。单独或组合使用的关键词是减肥手术、肥胖、维生素/矿物质缺乏、胃肠道功能改变、营养吸收、营养补充和代谢并发症,并在搜索列表中进行了各种组合。基于这篇综述,所有计划接受减肥手术的患者都应每天服用多种维生素和多种微量元素补充剂。文献表明,减肥手术后患者有以下营养物质缺乏的风险:维生素 B(12)、B(1)、C、叶酸、A、D 和 K,以及微量元素铁、硒、锌和铜。非处方多种维生素和矿物质补充剂不能提供足够的某些营养素,如维生素 B(12)、铁或脂溶性维生素,患者需要终身补充预防性补充剂,以维持最佳的微量营养素状态。此外,对于接受减肥手术的孕妇,需要进行适当的孕前保健,以进行充分的产前补充,因为铁、维生素 A、维生素 B(12)、维生素 K 和叶酸缺乏与母婴并发症有关,包括严重贫血、先天畸形、低出生体重和生长不良。所有减肥手术患者最好在手术后 3 个月开始定期监测血清营养素水平,并定期监测。