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1980-2005 年希腊女性乳腺癌死亡率的时间趋势:一项基于人群的研究。

Time trends of female breast cancer mortality in Greece during 1980-2005: a population based study.

机构信息

Department of Hygiene, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

出版信息

Postgrad Med J. 2010 Jul;86(1017):391-4. doi: 10.1136/pgmj.2009.091728. Epub 2010 Apr 3.

Abstract

BACKGROUND

Changes in female breast cancer mortality trends have been observed in recent years in western countries. The aim of the present study was to analyse breast cancer mortality in Greece, between 1980 and 2005.

METHODS

Time trends of breast cancer mortality were calculated per 100,000 women in the whole female population of Greece, in different age groups, and in different areas of the country. Mortality data and population age distribution were provided by the National Statistical Service of Greece.

RESULTS

Overall, female breast cancer mortality in Greece had an increasing trend during 1980-2005. Subgroup analysis according to age showed that this increase was confined to women older than 70 years. In contrast, a mild decrease was noted after the mid-1990s in women 40-69 years old. There were no notable regional differences in breast cancer mortality.

CONCLUSIONS

The increasing trend of breast cancer mortality in women aged 70 years and older could be attributed to limited use of secondary prevention methods and rare administration of systemic cytotoxic chemotherapy in these women. In contrast, implementation of these strategies could explain the recent reduction of breast cancer mortality in younger age groups.

摘要

背景

近年来,西方国家女性乳腺癌死亡率趋势发生了变化。本研究旨在分析希腊 1980 年至 2005 年期间乳腺癌的死亡率。

方法

通过希腊国家统计局提供的死亡率数据和人口年龄分布,计算了希腊整个人群中不同年龄组和不同地区每 10 万名女性的乳腺癌死亡率。

结果

总体而言,希腊女性乳腺癌死亡率在 1980 年至 2005 年间呈上升趋势。根据年龄进行的亚组分析表明,这种增长仅限于 70 岁以上的女性。相比之下,40-69 岁的女性在 20 世纪 90 年代中期以后死亡率略有下降。乳腺癌死亡率没有明显的地区差异。

结论

70 岁及以上女性乳腺癌死亡率上升的趋势可能归因于这些女性中二级预防方法的应用有限,以及系统细胞毒性化疗的应用罕见。相比之下,这些策略的实施可能解释了较年轻年龄组最近乳腺癌死亡率的下降。

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