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脑膜炎球菌 C 群结合疫苗在加拿大的接种情况:我们已经取得了多大的进展?还有多远的路要走?

Meningococcal serogroup C conjugate vaccination in Canada: how far have we progressed? How far do we have to go?

机构信息

Canadian Center for Vaccinology, IWK Health Centre and Dalhousie University, Halifax, NS.

出版信息

Can J Public Health. 2010 Jan-Feb;101(1):12-4. doi: 10.1007/BF03405553.

DOI:10.1007/BF03405553
PMID:20364530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6973578/
Abstract

Since routine meningococcal C conjugate vaccination was introduced into Canada in 2002, there have been a large regional variation in the routine programs, changes to the timing of the infant series in some provinces, and wide differences in catch-up programs. As immunization is viewed as a provincial responsibility, less attention has been paid to determining national coverage rates and the direct and indirect effects of the widely varying provincial/territorial vaccination programs on the nation as a whole. Canada's disjointed regional immunization campaigns leave the population at risk of disease for an extended length of time. The United Kingdom has proven that with a pro-active approach to planning, coordination, and implementation of a national immunization program, excellent long-term control of invasive meningococcal disease in a large population could be achieved in as little as one year. A summation of the current meningococcal immunization strategies used in Canada and an estimate of overall vaccine coverage of children and youth is provided.

摘要

自 2002 年加拿大常规接种脑膜炎球菌 C 结合疫苗以来,常规方案在地区间存在较大差异,一些省份调整了婴儿系列疫苗的接种时间,且补种计划也存在很大差异。由于免疫接种被视为省级责任,因此对确定全国覆盖率以及各省/地区接种计划对整个国家的直接和间接影响的关注度较低。加拿大支离破碎的区域免疫运动使民众面临疾病的风险时间延长。英国已经证明,通过积极主动的方法规划、协调和实施国家免疫计划,可以在短短一年内实现对大量人群侵袭性脑膜炎球菌病的长期有效控制。本文总结了加拿大目前使用的脑膜炎球菌免疫策略,并估计了儿童和青少年的总体疫苗覆盖率。

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An update on the invasive meningococcal disease and meningococcal vaccine conjugate recommendations. An Advisory Committee Statement (ACS).侵袭性脑膜炎球菌病及脑膜炎球菌结合疫苗建议的最新情况。一份咨询委员会声明(ACS)。
Can Commun Dis Rep. 2009 Apr;35(ACS-3):1-40.
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The impact of childhood meningococcal serogroup C conjugate vaccine programs in Canada.加拿大儿童C群脑膜炎球菌结合疫苗计划的影响
Pediatr Infect Dis J. 2009 Mar;28(3):220-4. doi: 10.1097/INF.0b013e31819040e7.
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Rapid identification of herd effects with the introduction of serogroup C meningococcal conjugate vaccine in Ontario, Canada, 2000-2006.2000 - 2006年在加拿大安大略省引入C群脑膜炎球菌结合疫苗后群体效应的快速识别
Vaccine. 2009 Mar 10;27(11):1735-40. doi: 10.1016/j.vaccine.2009.01.026. Epub 2009 Jan 30.
4
Impact of routine immunization using meningococcal C conjugate vaccine on invasive meningococcal disease in British Columbia.使用脑膜炎球菌C结合疫苗进行常规免疫接种对不列颠哥伦比亚省侵袭性脑膜炎球菌病的影响。
Can J Public Health. 2008 Sep-Oct;99(5):380-2. doi: 10.1007/BF03405245.
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